The COVID-19 pandemic has had an enormous and long-term impact on education systems across the nation. Consequently, many colleges and universities adopted a verity of different instructional strategies and new policies to mitigate the effects of this transition on academic achievement, student learning, and emotional well-being. This instantaneous change to the new pedagogical models was likely to impact both students and instructors. In this study, a survey was conducted to analyze the effectiveness of adopting innovative teaching approaches in online and hybrid frameworks on students’ engagement, achievement, and attainment at Northern Kentucky University. Two statistical t-test and ANOVA test were performed to compare the results and demonstrate the significant differences between groups of data. In addition, the survey responses were correlated with grades in the subsequent semesters to determine efficacy. The result shows that incorporating active and interactive learning strategies can improve online learning experience of students. The responses indicate that introductory level and lab-based courses may benefit more from aforementioned strategies.