Perceptual Functioning

Giersch, Anne; Laprévote, Vincent

doi:10.1007/7854_2022_393

Cited by 3 publications

(2 citation statements)

References 262 publications

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“…Abnormal perception in schizophrenia is supported by research showing that individuals with schizophrenia perform visual tasks differently from healthy individuals. Often this abnormal performance consists-as observed for contrast detection-in exhibiting impaired performance (Butler, Silverstein, et al, 2008;Giersch & Laprévote, 2023;Yoon et al, 2013). In these cases, estimating lapses, which are non-perceptual errors caused by, for example, reduced alertness (Luck & Gold, 2023), could help discern whether impaired performance stems from altered perception rather than cognitive deficits like lacks of attention (Luck & Gold, 2023;Yoon et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

“…People with schizophrenia not only experience visual hallucinations (Waters et al, 2014) but also exhibit anomalies in the perception of visual stimuli (Butler, Silverstein, et al, 2008;Giersch & Laprévote, 2023;Yoon et al, 2013). Among these anomalies, there are deficits in perceiving basic features such as contrast (Slaghuis, 1998), color (Shuwairi et al, 2002), motion (Wertheim et al, 1985) and spatial frequency (O'Donnell et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

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A systematic review and meta-analysis on contrast sensitivity in schizophrenia

Linares,

Joostens,

de la Malla

2023

Preprint

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Understanding perceptual alterations in mental diseases can help uncover neural and computational anomalies. Contrast sensitivity, a widely used measure to evaluate visual function, has been reported as deficient in schizophrenia, but the evidence supporting this deficit has not been comprehensively synthesized. In our search, we identified 36 studies that measured contrast sensitivity in individuals with schizophrenia and healthy controls. The meta-analysis of these studies indicate a robust deficit (g = 0.66; 95% CI, 0.38 to 0.93). However, we have found evidence of the deficit being driven by medication, which suggests that it might not stem from the etiology of the disease. Furthermore, none of the studies controlled for task engagement so further research is needed to determine whether the deficit is genuinely perceptual.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A systematic review and meta-analysis on contrast sensitivity in schizophrenia

Linares,

Joostens,

de la Malla

2023

Preprint

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The involvement of the cerebellar vermis across the psychotic-affective spectrum in enriched samples of recent-onset schizophrenia, bipolar disorder, and major depressive disorder

Xiao,

Kandala,

Huang

et al. 2025

Journal of Psychiatric Research

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A Systematic Review and Meta-Analysis on Contrast Sensitivity in Schizophrenia

Linares,

Joostens,

de la Malla

2024

Schizophrenia Bulletin

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Background and Hypothesis Understanding perceptual alterations in mental disorders can help uncover neural and computational anomalies. In schizophrenia, perceptual alterations have been reported for many visual features, including a deficit in contrast sensitivity, a key measure of visual function. The evidence supporting this deficit, however, has not been comprehensively synthesized. Study Design We conducted a systematic review and meta-analysis of studies measuring contrast sensitivity in individuals with schizophrenia and healthy controls. Our search identified 46 studies, of which 43 focused on chronic patients. Study Results We found that patients with chronic schizophrenia have reduced contrast sensitivity (g = 0.74; 95% CI, 0.55 to 0.93; P = 8.2 × 10−10). However, we found evidence that the deficit could be driven by medication. Additionally, none of the studies estimated attentional lapses, leaving it uncertain whether a potentially higher frequency of lapses in patients contributes to the observed deficit. Furthermore, only two studies comprehensively assessed visual acuity, complicating the understanding of the role of spatial frequency in the observed deficit. Conclusions While we identified a robust deficit in contrast sensitivity among chronic schizophrenia patients, the influence of attentional lapses and medication on this impairment remains unclear. We make several suggestions for future research to clarify the underlying mechanisms contributing to this deficit.

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Perceptual Functioning

Cited by 3 publications

References 262 publications

A systematic review and meta-analysis on contrast sensitivity in schizophrenia

A systematic review and meta-analysis on contrast sensitivity in schizophrenia

The involvement of the cerebellar vermis across the psychotic-affective spectrum in enriched samples of recent-onset schizophrenia, bipolar disorder, and major depressive disorder

A Systematic Review and Meta-Analysis on Contrast Sensitivity in Schizophrenia

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