Visual salience detection originated over 500 million years ago and is one of nature's most efficient mechanisms. In contrast, many state-of-the-art computational saliency models are complex and inefficient. Most saliency models process high-resolution color (HC) images; however, insights into the evolutionary origins of visual salience detection suggest that achromatic low-resolution vision is essential to its speed and efficiency. Previous studies showed that lowresolution color and high-resolution grayscale images preserve saliency information. However, to our knowledge, no one has investigated whether saliency is preserved in low-resolution grayscale (LG) images. In this study, we explain the biological and computational motivation for LG, and show, through a range of human eye-tracking and computational modeling experiments, that saliency information is preserved in LG images. Moreover, we show that using LG images leads to significant speedups in model training and detection times and conclude by proposing LG images for fast and efficient salience detection.Recently, deep neural networks have achieved state-of-the-art performance on various saliency benchmarks [9,10,11,12]. Nevertheless, this success comes at high computational costs [13,14]. Training and running these networks is time-and resourceintensive, which is not easily scalable to resource-limited devices [13]. Processing highresolution or stacked multi-resolution color images is resource-intensive and contributes to this limitation [15]. In contrast, natural visual salience detection proves to be much more efficient. A deeper understanding of the evolutionary origins of visual salience detection suggests that bottom-up saliency is computed from achromatic low-resolution information [16].Previous studies have shown that low-resolution color (LC) [17,18,19] and highresolution grayscale (HG) [20,21,22,23,24,25] images preserve saliency information, yet are significantly more computationally attractive than high-resolution color (HC) images. Low-resolution grayscale (LG) images are even more computationally attractive, compared to LC and HG images. Nevertheless, to our knowledge, no one has investigated whether saliency information is preserved in LG images. In this study, we therefore investigate saliency preservation in LG images, and present the following three contributions: (1) linking low-resolution grayscale information with the bio-inspired evolutionary origins of visual saliency, (2) assessing the preservation of saliency information in low-resolution grayscale images, and (3) proposing low-resolution grayscale images for fast and efficient saliency detection. Therefore, based on a deeper understanding of the evolutionary origins of visual saliency, together with knowledge gained from studies investigating salience preservation in LC and HG images, we hypothesize that saliency information is well-preserved in LG images.