Percutaneous Absorption of UV Filters Contained in Sunscreen Cosmetic Products

González, Zacarías León

doi:10.1007/978-3-319-01189-9

Cited by 2 publications

(2 citation statements)

References 48 publications

(70 reference statements)

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“…Organic filter lipophilicity is the main characteristic that allows passing the skin barrier. At the systemic level, these compounds can undergo biotransformation processes in the organism (González, 2014;Hiller et al, 2019). Compounds such as 4-aminobenzoic acid, homosalate, oxybenzone, octinoxate, octyl salicylate and camphorderived filters have been attributed to systemic absorption and estrogenic activity (Gilbert et al, 2013;Kockler et al, 2012;Mancebo, Hu, Wang, 2014;Siller et al, 2018).…”

Section: Conventional Photo-protectionmentioning

confidence: 99%

Algae Metabolites as an Alternative in Prevention and Treatment of Skin Problems Associated with Solar Radiation and Conventional Photo-protection

Rincón-Valencia

Mejía-Giraldo

Puertas‐Mejía

2022

Braz. J. Pharm. Sci.

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Skin is the largest and heaviest organ in the human body also one of the most important and act as a barrier that separates our organism from the environment. The nature of this cover is physical, chemical, and immunological. It controls the flow of substances between the environment and the body. Skin pH between 5-7 works as a chemical barrier that helps to maintain its integrity and natural microbiota (Dragicevic, Maibach, 2015).Langerhans cells, dermal dendritic cells and macrophages are specialized skin cells that make the skin an immunecompetent organ (Dragicevic, Maibach, 2015;Wiznia, Elbuluk, 2017). The skin carries out metabolic functions like vitamin D synthesis. Furthermore, thermo-regulation, excretion, endocrine and sensitivity are other functions performed by the skin. (Dragicevic, Maibach 2015) The histological structure of the skin consists of a complex architecture that has three fundamental layers: epidermis, dermis and hypodermis (Figure 1A). The epidermis is the outermost layer. (Wiznia, Elbuluk, 2017) The main constituent cells of this layer are keratinocytes corresponding to 95 %, the remaining 5 % of the cells are melanocytes, Langerhans cells and dermal dendritic cells (Dragicevic, Maibach, 2015;Wiznia, Elbuluk, 2017) Melanocytes fulfill the production of melanin, which is the main endogenous defense of the skin to protect us against UV-radiation (UVR) (Norman, Menendez, 2008). The dermis is the second layer of the skin and is thicker

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Section: Conventional Photo-protectionmentioning

confidence: 99%

Algae Metabolites as an Alternative in Prevention and Treatment of Skin Problems Associated with Solar Radiation and Conventional Photo-protection

Rincón-Valencia

Mejía-Giraldo

Puertas‐Mejía

2022

Braz. J. Pharm. Sci.

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“…The role of hypodermis is to connect the dermis with the muscle and bones via septa, a connective tissue. It contains blood vessel and nerves (González, 2013).…”

Section: Hypodermismentioning

confidence: 99%

Developing a zebrafish model of epidermolysis bullosa

Kahsay¹

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Percutaneous Absorption of UV Filters Contained in Sunscreen Cosmetic Products

Cited by 2 publications

References 48 publications

Algae Metabolites as an Alternative in Prevention and Treatment of Skin Problems Associated with Solar Radiation and Conventional Photo-protection

Algae Metabolites as an Alternative in Prevention and Treatment of Skin Problems Associated with Solar Radiation and Conventional Photo-protection

Developing a zebrafish model of epidermolysis bullosa

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