Percutaneous aortic valve replacement: An experimental study. I. Studies on implantation

Abstract

Aortic valved stents can be successfully implanted without thoracotomy by using a transluminal catheter technique. Long-term function of the valves remains to be established.

ECG Abnormalities after Transcatheter Aortic Valve Implantation

“…However, neither has been shown to reduce long-term mortality with a one-and 5-year survival of 60% and 32%, respectively (6)(7)(8). A less invasive treatment option for patients with severe aortic stenosis was pioneered by Andersen et al (9) and, subsequently, the feasibility of percutaneous prosthetic valve delivery was demonstrated by others (10)(11)(12)(13)(14). Transcatheter aortic valve implantation (TAVI) was developed one decade ago to minimize surgical risk in high-risk patients with severe symptomatic aortic stenosis refused for conventional open aortic valve replacement.…”

Percutaneous aortic valve replacement: more than palliation?

“…When the desired position in the diseased aortic valve anulus [15] is reached, the valved stent must be expanded to match that of the anulus and does not compromise coronary blood flow [15,16]. Furthermore, the valve prosthesis must have an anchoring mechanism allowing permanent fixation [14,15]. Before deployment of the valved stent, either the diseased stenotic aortic valve must be predilated [15], or ablated and removed [14].…”

“…Before deployment of the valved stent, either the diseased stenotic aortic valve must be predilated [15], or ablated and removed [14]. It is imperative that such an implant provides adequate hemodynamics [11][12][13][14][15]. Several investigators have made progress towards implanting percutaneous aortic valves in humans, especially over the past decade in animal experiments.…”

“…Furthermore, the valve prosthesis must have an anchoring mechanism allowing permanent fixation [14,15]. Before deployment of the valved stent, either the diseased stenotic aortic valve must be predilated [15], or ablated and removed [14]. It is imperative that such an implant provides adequate hemodynamics [11][12][13][14][15].…”

“…For reprint orders, please contact reprints@future-drugs.com which is mounted on an expandable valved stent [11], which can be folded to a diameter less than 22 F and delivered percutaneously via standard catheter-based techniques [12] and implanted [13,14]. When the desired position in the diseased aortic valve anulus [15] is reached, the valved stent must be expanded to match that of the anulus and does not compromise coronary blood flow [15,16].…”