Percutaneous Aspiration Thrombectomy in Treatment of Massive Pulmonary Embolism

Abstract

This study demonstrates safety and effectiveness of percutaneous mechanical aspiration thrombectomy in patients with massive PE with a large thrombus burden.

Percutaneous suction thrombectomy of large tumor thrombus causing massive pulmonary embolism

“…Rheolytic aspiration thrombectomy carries a black box warning for use in pulmonary embolus in spite of several small case series describing the efficacy of rheolytic aspiration thrombectomy for PE 6 . Continuous aspiration thrombectomy has been shown to be feasible for more conventional PE in small case series and represents the only alternative when open thrombectomy, CDT, or systemic thrombolysis is contraindicated 7, 8, 9…”

“…Whereas IVC tumor thrombosis is common in patients with locally advanced RCC, massive embolism is a rare occurrence 8 . In a retrospective analysis, of 13 patients treated with large IVC tumor thrombus associated with RCC, only one patient had a documented embolism of the tumor thrombus 10 .…”

Effective Treatment of Intermediate-Risk Pulmonary Embolism by Manual Thrombus Aspiration. A Report of Two Cases

“…In our experience, in the presence of contraindications to systemic thrombolysis, the degree of refractory hypoxaemia and RV dysfunction at presentation are a solid indication. Moreover, as a previous study demonstrated, percutaneous mechanical aspiration thrombectomy in patients with massive PE with large thrombus burden is safe and effective [6].…”

The Efficacy of Rotational Thrombectomy on the Mortality of Patients with Massive and Submassive Pulmonary Embolism

“…Although systemic anticoagulation remains the cornerstone of therapy for acute symptomatic pulmonary embolism, the morbidity and mortality associated with massive pulmonary embolism (MPE) and submassive pulmonary embolism (SPE) warrant treatment beyond anticoagulation alone. More aggressive therapeutic options include systemic intravenous thrombolysis, surgical embolectomy, catheter‐directed intra‐arterial thrombolysis, and percutaneous mechanical thrombectomy (PMT) . Despite major advancements in endovascular technology, the role of PMT in the treatment of acute pulmonary embolism remains undefined.…”

“…More aggressive therapeutic options include systemic intravenous thrombolysis, surgical embolectomy, catheter-directed intraarterial thrombolysis, and percutaneous mechanical thrombectomy (PMT). 6,7 Despite major advancements in endovascular technology, the role of PMT in the treatment of acute pulmonary embolism remains undefined.…”