Percutaneous Closure of Paravalvular Leak After Transcatheter Aortic Valve Replacement

Luu, Jane T.; Farouk, Omar; Feldman, Ted; Price, Matthew J.

doi:10.1016/j.jcin.2012.08.026

Cited by 15 publications

(9 citation statements)

References 1 publication

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“…Another two series of 5 patients each with at least moderate PVL after TAVR with a self‐expandable valve reported successful PVL repair in all patients with no adverse events . There are several other reports that reported cases of successful repair of the PVL after TAVR . None of these studies have systematically evaluated follow‐up outcome of PVL repair in post‐TAVR patients.…”

Section: Discussionmentioning

confidence: 99%

Outcome of paravalvular leak repair after transcatheter aortic valve replacement with a balloon‐expandable prosthesis

Dhoble

Chakravarty

Nakamura

et al. 2016

Cathet Cardio Intervent

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Section: Discussionmentioning

confidence: 99%

Outcome of paravalvular leak repair after transcatheter aortic valve replacement with a balloon‐expandable prosthesis

Dhoble

Chakravarty

Nakamura

et al. 2016

Cathet Cardio Intervent

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“…Three patients who had the same-day procedure 13,14,16 and those with no description of the time from TAVI to PCC procedure 17,18 were removed from analysis. Overall, the time from TAVI to PCC procedure was 321 ± 371 days (range, 3-1506 days).…”

Section: Discussionmentioning

confidence: 99%

Percutaneous Closure of Paravalvular Regurgitation After Transcatheter Aortic Valve Implantation: A Systematic Review

Ando

Takagi

2016

Clinical Cardiology

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Paravalvular regurgitation (PVR) remains one of the drawbacks of transcatheter aortic valve implantation (TAVI). Details of percutaneous closure (PCC) of PVR after TAVI remain obscure. We aimed to explore the patient characteristics, procedural details, closure devices used, and outcomes of PCC after TAVI. A systematic search of the MEDLINE/PubMed and Embase databases from January 2002 to September 2015 was conducted. Reports considered to include same patient were excluded and only the studies with largest cohorts were included. A total of 14 studies including 58 patients (61 cases) were included in the study. A balloonexpandable (BE) valve was used more frequently compared with a self-expandable (SE) valve (72.6% vs 27.4%, respectively). The mean success rate was 86.9% (100% and 77.8%, respectively; P = 0.097). The median number of closure devices used was 1 (range, 1-4) and did not differ between SE and BE valves (P = 0.71). Mean time from index procedure to PCC did not differ between SE and BE valves (295 ± 380 days vs 379 ± 353 days; P = 0.71). Seven patients had history of valve-in-valve and 6 patients had procedural success. Among the patients with available follow-up data (94.8%), there were 15 deaths (27.3%). Percutaneous closure of PVR after TAVI had a high success rate in selected patients in both BE and SE valves. The success rate, timing, and number of closure devices were similar between BE and SE valves. However, prognosis remains fairly poor.

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“…According to Luu et al [6], the PVL is referred to as a small opening between the aortic annulus and prosthetic valve, where the blood flowed through the uncovered portion of the stent frame. is complication occurred due to underexpansion of the prosthetic valve, undersizing, interference with stent expansion due the impingement of calcium nodules, and malpositioning of the valve [6,7]. Lerakis et al [8] stated that the PVL remains a frequent issue after implantation, which can be graded as mild (7.8%-40.8%), moderate (5%-36.9%), and severe (0.5%-13.6%).…”

Section: Introductionmentioning

confidence: 99%

Fluid Structure Interaction on Paravalvular Leakage of Transcatheter Aortic Valve Implantation Related to Aortic Stenosis: A Patient-Specific Case

Basri

Zuber

Basri

et al. 2020

Computational and Mathematical Methods in Medicine

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This study investigated the impact of paravalvular leakage (PVL) in relation to the different valve openings of the transcatheter aortic valve implantation (TAVI) valve using the fluid structure interaction (FSI) approach. Limited studies were found on the subject of FSI with regards to TAVI-PVL condition, which involves both fluid and structural responses in coupling interaction. Hence, further FSI simulation with the two-way coupling method is implemented to investigate the effects of hemodynamics blood flow along the patient-specific aorta model subjected to the interrelationship between PVL and the different valve openings using the established FSI software ANSYS 16.1. A 3D patient-specific aorta model is constructed using MIMICS software. The TAVI valve identical to Edward SAPIEN XT 26 (Edwards Lifesciences, Irvine, California), at different Geometrical Orifice Areas (GOAs), is implanted into the patient’s aortic annulus. The leaflet opening of the TAVI valve is drawn according to severity of GOA opening represented in terms of 100%, 80%, 60%, and 40% opening, respectively. The result proved that the smallest percentage of GOA opening produced the highest possibility of PVL, increased the recirculatory flow proximally to the inner wall of the ascending aorta, and produced lower backflow velocity streamlines through the side area of PVL region. Overall, 40% GOA produced 89.17% increment of maximum velocity magnitude, 19.97% of pressure drop, 65.70% of maximum WSS magnitude, and a decrement of 33.62% total displacement magnitude with respect to the 100% GOA.

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Percutaneous Closure of Paravalvular Leak After Transcatheter Aortic Valve Replacement

Cited by 15 publications

References 1 publication

Outcome of paravalvular leak repair after transcatheter aortic valve replacement with a balloon‐expandable prosthesis

Outcome of paravalvular leak repair after transcatheter aortic valve replacement with a balloon‐expandable prosthesis

Percutaneous Closure of Paravalvular Regurgitation After Transcatheter Aortic Valve Implantation: A Systematic Review

Fluid Structure Interaction on Paravalvular Leakage of Transcatheter Aortic Valve Implantation Related to Aortic Stenosis: A Patient-Specific Case

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