Percutaneous Collagen Induction Therapy: An Alternative Treatment for Scars, Wrinkles, and Skin Laxity

Aust, Matthias; Fernandes, Des; Kolokythas, P.; Kaplan, Hilton M.; Vogt, Peter M.

doi:10.1097/01.prs.0000304612.72899.02

Cited by 297 publications

(250 citation statements)

References 35 publications

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“…10 In our study, we observed that many patients in group "A" reported improvement in the firmness of the face giving a lifted appearance which was intact for months even after the completion of the study. This effect was also reported in other studies such as that by Imran et al and Aust et al The firmness was probably due to continuation of deposition of collagen and elastin upto 6 months after the procedure which was confirmed histologically in the study done by Aust et al 11 This lifted appearance provided extra anti-aging effects in our patients. Microneedling can provide both acne scar remodelling and anti-aging benefits in same sitting.…”

Section: Discussionsupporting

confidence: 77%

Microneedling vs. chemical reconstructon of skin scars with trichloroacetic acid: a comparative study

Dhollan

Thirunavukkarasu

2017

Int J Res Dermatol

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Background: Acne scars are a cause of major psychological morbidity in the young population. Microneedling using dermarollers which uses the principle of percutaneous collagen induction and Chemical reconstruction of skin scars (CROSS) using Trichloroacetic acid (TCA) are both widely used methods for the treatment of acne scars and are cheaper alternatives to LASER resurfacing. The aim of our study is to objectively compare the efficacy of microneedling using dermaroller with CROSS using 100% TCA in the management of acne scars.Methods: 30 patients with acne scars were divided into 2 groups A and B with 15 patients each. Group ‘A’ underwent microneedling using 1.5 mm dermaroller and Group ‘B’ underwent CROSS technique with 100% TCA. A total of 4 sessions at monthly intervals were performed on both groups. The percentage improvement in the acne scar grade between the two groups was compared using the student ‘t’ test.Results: Among the 30 patients, 13 (86%) patients in Group A (Microneedling) and 11 (78%) patients in group B (CROSS) noted significant reduction in their acne scar grade. The difference between the 2 groups was statistically insignificant. 3 patients had significant post inflammatory hyperpigmentation in group ‘B’.Conclusions: The techniques of microneedling and CROSS are both effective in acne scars But microneedling scores in other aspects such as faster wound healing, better skin rejuvenation and safety in dark skinned individuals.

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Section: Discussionsupporting

confidence: 77%

Microneedling vs. chemical reconstructon of skin scars with trichloroacetic acid: a comparative study

Dhollan

Thirunavukkarasu

2017

Int J Res Dermatol

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“…In microneedling with dermaroller, there are fine needles which puncture the skin and cause increased elastin and collagen content in the dermis, collagen remodeling and increase in thickness of epidermis and dermis. 15 In subcision a small needle is inserted beneath the scar to loosen the fibrotic adhesions. Along with loosening of tissue there is also some bleeding at the site which creates a potential space where collagen can be deposited during the wound healing phase CO 2 lasers have a selectivity for water and it has a double effect that is, they promote the wound healing process and arouse an amplified production of myo-fibroblasts and matrix proteins such as hyaluronic acid.…”

Section: Introductionmentioning

confidence: 99%

A study of efficacy of subcision, micro-needling and carbon dioxide fractional laser for treatment of acne scars

2016

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“…In addition, new capillaries are formedthis neovascularisation and neocollagenesis following treatment leads to reduction of scars. [3][4][5] The procedure was therefore aptly called "percutaneous collagen induction therapy" and has also been used in the treatment of photoageing.…”

Section: Discussionmentioning

confidence: 99%

Dermaroller: simple and effective acne scar treatment

Patil

2016

Int J Res Dermatol

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Background: Scarring is particularly a distressing phenomenon. The micro-needling is a minimally invasive procedure which has recently attained popularity because of the fact that it can be used safely with minimal training.Methods: The present study was performed on 30 patients suffering from facial scarring of acne vulgaris. The patients were photographed and assessed clinically at the time of enrolment to grade the severity of scarring as per the grading system proposed by Goodman and Baron.Results: A total of 30 patients were included in the study of which females were 18 and males 12. The age of the patients ranged from 18 to 30 years with the mean age of 24 years. Overall, 20 out of the total of 28 patients (71.4%) showed an excellent response to dermaroller treatment while 7 others achieved a good response (25%). Only 1 patient (3.6%) out of the total of 28 failed to show a significant response to treatment.Conclusions: Dermaroller is a safe and effective treatment option for grade 2 and grade 3 acne scars.

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Percutaneous Collagen Induction Therapy: An Alternative Treatment for Scars, Wrinkles, and Skin Laxity

Cited by 297 publications

References 35 publications

Microneedling vs. chemical reconstructon of skin scars with trichloroacetic acid: a comparative study

Microneedling vs. chemical reconstructon of skin scars with trichloroacetic acid: a comparative study

A study of efficacy of subcision, micro-needling and carbon dioxide fractional laser for treatment of acne scars

Dermaroller: simple and effective acne scar treatment

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