“…15,59 Techniques targeting different locations along the afferent pain pathway have been used for an array of pain conditions. 60,61,104,105 In addition to the anterolateral quadrant of the spinal cord, other targets of destructive surgery have included the following: the sensory and sympathetic ganglia; the dorsal and ventral spinal roots; the DREZ; and the decussating extralemniscal fibers. Despite their long history and purported efficacy, the use of destructive techniques has generally declined in modern practice, although there are a few notable exceptions.…”