Percutaneous Coronary Intervention Vs Coronary Artery Bypass Surgery for Unprotected Left Main Coronary Disease: G-LM Registry

Daoulah, Amin; Alasmari, Abdulaziz; Hersi, Ahmad; Alshehri, Mohammed; Garni, Turki Al; Abuelatta, Reda; Amin, Haitham; Almahmeed, Wael; Aljohar, Alwaleed; Abumelha, Bader K.; Alzahrani, Badr; Ghani, Mohamed Ajaz; Yousif, Nooraldaem; Hashmani, Shahrukh; Al-Faifi, Salem M.; Kazim, Hameedullah M.; Refaat, Wael; Dahdouh, Ziad; Khaliel, Feras; Aithal, Jairam; Elmahrouk, Ahmed F.; Ibrahim, Ahmed M.; Elganady, Abdelmaksoud; Qutub, Mohammed A; Alama, Mohamed Nabil; Abohasan, Abdulwali; Hassan, Taher; Balghith, Mohammed; Alqahtani, Abdulrahman M; Abdelaziz, Ahmed F; Altnji, Issam; Hussien, Adnan Fathey; Abdulhabeeb, Ibrahim A M; Ahmad, Osama; Haddara, Mamdouh; Alqahtani, Abdulrahman; Alshahrani, Saif S.; Qenawi, Wael; Izzeldin, Mohamed H; El-Sayed, Osama; Jamjoom, Ahmed; Moghairi, Abdulrahman Al; Amri, Hussein Al; Ibrahim, Waleed Moubark; Alarbash, Mohsen; Hussain, Tajammul; Shamsi, Fahad; Selim, Ehab; Ramadan, Mohamed; Alsergani, Hani; Mohamed, Tarek; Khalifa, Abdulwahab Al; Hiremath, Niranjan; Ibrahim, Amira Ali Taha; Abdallah, Hassane; Elprince, Amr; Diab, Ahmed; Seoud, Diaa Eldin A; Al‐Ghamdi, Ahmed A.; Al‐Ebrahim, Khaled E.; Basudan, Duna; Nasser, Faisal Omar M Al; Ali, Ibrahim Ahmed Abuagila; Shawky, Abeer M.; Ghonim, Ahmed A.; Feteih, Maun; Abualnaja, Seraj; Alhaddadi, Bandar; Alhamid, Sameer; Ahmed, Waleed; Jafary, Zainab M.; Ahnia, Samir; Gasem, Jala; Alaydarous, Shahad; Khatab, Tamer; Mohamed, Ataaelrahman; Maghrabi, Mohamed; Samadi, Faisal Al; Kannout, Tareef H; Mahrous, Najeeb; Almaleh, Yahya; Riyami, Adil B Al; Yousef, Altayyeb; Ahmed, Mohammed; Ahmed, Ruqayyah Ali; Tawfik, Wael; Almegreb, Nasser; Faden, Mazen; Haq, Ejazul; Al-Otaibi, Salah N.; Eldesoky, Akram; Clarkson, Francis A.; Lotfi, Amir

doi:10.1016/j.cpcardiol.2021.101002

Cited by 8 publications

(5 citation statements)

References 27 publications

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“…The Gulf left-main registry contains data about LMCA revascularization with either PCI or CABG from 14 cardiac centers in the Gulf Area [ 6 , 7 ]. Patients were recruited from January 2015 to December 2019.…”

Section: Methodsmentioning

confidence: 99%

Percutaneous coronary intervention vs. coronary artery bypass grafting in emergency and non-emergency unprotected left-main revascularization

Daoulah,

Alqahtani,

Elmahrouk

et al. 2023

Eur J Med Res

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Background The optimal revascularization strategy in patients with left main coronary artery (LMCA) disease in the emergency setting is still controversial. Thus, we aimed to compare the outcomes of percutaneous coronary interventions (PCI) vs. coronary artery bypass grafting (CABG) in patients with and without emergent LMCA disease. Methods This retrospective cohort study included 2138 patients recruited from 14 centers between 2015 and 2019. We compared patients with emergent LMCA revascularization who underwent PCI (n = 264) to patients who underwent CABG (n = 196) and patients with non-emergent LMCA revascularization with PCI (n = 958) to those who underwent CABG (n = 720). The study outcomes were in-hospital and follow-up all-cause mortality and major adverse cardiovascular and cerebrovascular events (MACCE). Results Emergency PCI patients were older and had a significantly higher prevalence of chronic kidney disease, lower ejection fraction, and higher EuroSCORE than CABG patients. CABG patients had significantly higher SYNTAX scores, multivessel disease, and ostial lesions. In patients presenting with arrest, PCI had significantly lower MACCE (P = 0.017) and in-hospital mortality (P = 0.016) than CABG. In non-emergent revascularization, PCI was associated with lower MACCE in patients with low (P = 0.015) and intermediate (P < 0.001) EuroSCORE. PCI was associated with lower MACCE in patients with low (P = 0.002) and intermediate (P = 0.008) SYNTAX scores. In non-emergent revascularization, PCI was associated with reduced hospital mortality in patients with intermediate (P = 0.001) and high (P = 0.002) EuroSCORE compared to CABG. PCI was associated with lower hospital mortality in patients with low (P = 0.031) and intermediate (P = 0.001) SYNTAX scores. At a median follow-up time of 20 months (IQR: 10–37), emergency PCI had lower MACCE compared to CABG [HR: 0.30 (95% CI 0.14–0.66), P < 0.003], with no significant difference in all-cause mortality between emergency PCI and CABG [HR: 1.18 (95% CI 0.23–6.08), P = 0.845]. Conclusions PCI could be advantageous over CABG in revascularizing LMCA disease in emergencies. PCI could be preferred for revascularization of non-emergent LMCA in patients with intermediate EuroSCORE and low and intermediate SYNTAX scores.

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Section: Methodsmentioning

confidence: 99%

Percutaneous coronary intervention vs. coronary artery bypass grafting in emergency and non-emergency unprotected left-main revascularization

Daoulah,

Alqahtani,

Elmahrouk

et al. 2023

Eur J Med Res

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show abstract

Section: Methodsmentioning

confidence: 99%

“…We included patients with ULMCA disease treated with PCI (1222) or CABG (916). The remaining 519 patients were excluded 12 . All PCIs were exclusively performed using drug-eluding stents (DES) across all centres.…”

Section: Methodsmentioning

confidence: 99%

“…The detailed information regarding the design, methods including the selection criteria for PCI versus CABG for the study populations, end points, and relevant definitions are outlined in the Gulf Left Main Registry. 12 This was a multicentre, retrospective, observational study comparing PCI and CABG in patients with ULMCA disease conducted from January 2015 to December 2019 for all cases with LMCA from 14 centres across 3 Gulf countries: the Kingdom of Saudi Arabia (KSA), the United Arab Emirates (UAE), and the Kingdom of Bahrain. Patients with significant LMCA disease were identified accordingly using catheterization laboratory (Cath lab) logbooks or electronic databases.…”

Section: Patient Datamentioning

confidence: 99%

“…The remaining 519 patients were excluded. 12 All PCIs were exclusively performed using drug-eluding stents (DES) across all centres.…”

Section: Patient Datamentioning

confidence: 99%

See 2 more Smart Citations

Impact of left ventricular ejection fraction on outcomes after left main revascularization: g-LM Registry

Daoulah

Naser

Hersi

et al. 2022

Journal of Cardiovascular Medicine

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Aims The impact of left ventricular dysfunction on clinical outcomes following revascularization is not well established in patients with unprotected left main coronary artery disease (ULMCA). In this study, we evaluated the impact of left ventricular ejection fraction (LVEF) on clinical outcomes of patients with ULMCA requiring revascularization with percutaneous coronary intervention (PCI) compared with coronary artery bypass graft (CABG).

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Outcomes of Myocardial Revascularization in Diabetic Patients With Left Main Coronary Artery Disease: A Multicenter Observational Study From Three Gulf Countries

Daoulah

Elfarnawany

Garni

et al. 2023

Cardiovascular Revascularization Medicine

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Percutaneous Coronary Intervention Vs Coronary Artery Bypass Surgery for Unprotected Left Main Coronary Disease: G-LM Registry

Cited by 8 publications

References 27 publications

Percutaneous coronary intervention vs. coronary artery bypass grafting in emergency and non-emergency unprotected left-main revascularization

Percutaneous coronary intervention vs. coronary artery bypass grafting in emergency and non-emergency unprotected left-main revascularization

Impact of left ventricular ejection fraction on outcomes after left main revascularization: g-LM Registry

Outcomes of Myocardial Revascularization in Diabetic Patients With Left Main Coronary Artery Disease: A Multicenter Observational Study From Three Gulf Countries

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