“…Local ablative therapy has been applied for symptom palliating in patients with advanced tumors of the lung (80), kidney, bone (81), pancreas, and bile duct (82), as well as liver cancer with a small mass or at special sites where the tumor is directly abutting surrounding structures (such as the liver capsule, gallbladder, vessel, diaphragm, intestine, and adrenal gland), with a maximum distance of 1.0 cm between the tumor and these organs (83). It has also been utilized in the treatment of some benign lesions like osteoid osteomas (84-86), uterine fibroids, Morton's neuroma (87), skin lesions (88), and varicose veins.…”