Percutaneous Cryotherapy for Treatment of Chondroblastoma: Early Experience

Thibaut, Antoine; Bouhamama, Amine; Boespflug, Amélie; Vaz, Gualter; Cuinet, M.; Kalenderian, Anne-Charlotte; Menassel, Badis; Ricoeur, Alexis; Mastier, Charles; Pilleul, F.

doi:10.1007/s00270-018-2085-y

Cited by 11 publications

(12 citation statements)

References 8 publications

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“…Our rate of recurrence of 2.8% is lower than that reported in other studies which have also included adjuvant techniques such as fluid nitrogen cryopreservation, phenolization and radiofrequency ablation [12], [15], [22], [23]. Only 1 patient with distal femur chondroblastoma relapsed, 10 months post-operation.…”

Section: Discussioncontrasting

confidence: 62%

“…These complications also affected the prognosis. Adjuvant procedures such as cryosurgery or radiofrequency ablation were used in some patients [14], [15], [16], resulting in lower reoccurrence rates, but increases rates of cartilage injury and secondary osteoarthritis. The role of adjuvant treatments in the management of chondroblastoma needs to be clarified, as the risks associated with use of such agents must be weighed against the benefits.…”

Section: Discussionmentioning

confidence: 99%

“…Curettage, either alone or in conjunction with bone grafting using autogenous or allogeneic bone grafts or both, has been described in many studies, with a high local recurrence rate and development of secondary osteoarthritis [11], [12], [13]. Adjuvant procedures such as cryosurgery or radiofrequency ablation have been used in some patients [14], [15], [16], resulting a reduction in local recurrence rate but an increase in cartilage injury and secondary osteoarthritis rate.…”

Section: Introductionmentioning

confidence: 99%

“…However, management of lesions in the proximal tibia and distal femur is challenging because it is difficult to gain full access to intraepiphyseal lesions for completion of curettage [17]. After intralesional curettage, cryosurgery or radiofrequency ablation was used in some studies [14], [15], [16], packing with polymethylmethacrylate was also reported [11], [18]. These studies showed a lower rate of recurrence, but the complications associated with cartilage injury were high.…”

Section: Introductionmentioning

confidence: 99%

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Have the difficulties and complications of surgical treatment for chondroblastoma of the adjoining knee joint been overestimated?

Liu

Yuan

et al. 2019

Journal of Bone Oncology

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Background and objective Chondroblastoma is difficult to treat as the tumor is surrounded by both articular cartilage and the epiphyseal plate. The differences in joint shape further complicate the problem. This retrospective study evaluates the efficacy of intraregional aggressive curettage and allogeneic bone grafting for treating chondroblastoma of the adjoining knee joint. Methods From February 2010 to February 2017, 36 patients with chondroblastoma of the adjoining knee joint were identified. All patients were treated with intraregional aggressive curettage, phenolization, and allogeneic bone grafting. Follow-up for lesion healing, local recurrence, functional outcomes and secondary osteoarthritis were assessed both clinically and radiologically. Results Thirty-six patients (mean age 17 years) were enrolled with a mean follow-up of 51.8 months (18–98 months). The tumor locations were as follows: distal femur (14), proximal tibia (20), and patella (2). Only 1 patient relapsed, 10 months post-operation. All patients had good bone healing. No knee varus or valgus deformity developed. The mean Musculoskeletal Tumor Society functional score was 28.6 ± 1.1 post-operation. At the last follow-up, secondary osteoarthritis was found in 1 patient, the patient was asymptomatic. Conclusions Intraregional aggressive curettage, phenolization, and allogeneic bone grafting are effective for treatment of chondroblastoma of the adjoining knee joint.

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Section: Discussioncontrasting

confidence: 62%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Have the difficulties and complications of surgical treatment for chondroblastoma of the adjoining knee joint been overestimated?

Liu

Yuan

et al. 2019

Journal of Bone Oncology

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“…Postsurgical recurrence rates are found in 10 to 35% of cases. 54 For this reason, minimally invasive treatments including percutaneous RFA or CA 55,56 have been proposed, and successfully applied, with the latter being particularly effective in the prevention of chondral damage.…”

Section: Therapeutic Strategymentioning

confidence: 99%

French Multidisciplinary Approach for the Treatment of MSK Tumors

Cazzato

Garnon

Marini

et al. 2020

Semin Musculoskelet Radiol

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Several interventional treatments have recently been integrated into the therapeutic armamentarium available for the treatment of bone tumors. In some scenarios (e.g., osteoid osteoma), interventional treatments represent the sole and definitive applied treatment. Due to the absence of widely shared protocols and the complex multivariate scenarios underlying the clinical presentation of the remaining bone tumors including metastases, therapeutic strategies derived from a multidisciplinary tumor board are essential to provide effective treatments tailored to each patient. In the present review, we present the multidisciplinary therapeutic strategies commonly adopted for the most frequent bone tumors.

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