Percutaneous Electrical Muscle Stimulation Attenuates Postprandial Hyperglycemia in Obese and Pre-obese Japanese Men

Kimura, Tetsuya; Matsumoto, Koji; Kameda, Naoko; Tanaka, Satsuki; Hayashi, Tatsuya; Moritani, Toshio

doi:10.5432/ijshs.20090033

Cited by 11 publications

(16 citation statements)

References 11 publications

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“…The results showed that the postprandial glucose levels were lower in the MES trial than the control trial [14]. In our study, the MES potency did not appear to be high enough to increase glucose uptake in the skeletal muscle.…”

Section: Oxygen Consumption (Vo2)contrasting

confidence: 61%

Effects of Motor-level Electrical Stimulations on Postprandial Glucose Levels in Non-Diabetic Young Individuals

Huang¹

2017

J Nov Physiother Phys Rehabil

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Background and objectives: Motor-level electrical stimulation (MES) has been shown to improve glucose tolerance and glucose uptake in both animals and humans. Recently, MES has been shown to improve the blood glucose control in people with Type 2 Diabetes (T2D). There are several types of MES applied in physical therapy clinics. However, it is unknown what types of MES optimally decrease postprandial glucose level. The purpose of this study was to compare the effects of three different types of MES on postprandial glucose levels in healthy non-diabetic subjects. Methods: Twenty-eight subjects were randomly assigned to four groups: MES 1, MES 2, MES 3 and the control group. All subjects participated in an overnight fast of at least 8 hours and had their fasting blood glucose measured. Subjects were given a glucose supplement to drink within 10 minutes, rested in supine for 30 minutes then the second glucose level was measured. Subjects received a 30-minute MES treatment (except for the control group) followed by the third blood glucose level test. Subjects then rested an additional 30 minutes followed by obtaining the fi nal blood glucose measurement. VO2 levels were monitored every 30 seconds, and heart rate was monitored every 3 minutes throughout the 90 minute study. Results: There were no signifi cant differences between groups on glucose levels and heart rate throughout the study. The MES 2, Russian Current, demonstrated a statistically signifi cant increase of 10% in VO2 toward the end of treatment. Conclusions: In this preliminary study, MES seems to have no effects on lowering postprandial glucose levels in healthy non-diabetic subjects. However, Russian Current may have a potential for optimally simulating physical activity. Future research is required with a more extended sampling method, a larger sample size, more intensive MES experimental protocols and a continuous glucose monitoring technique.

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Section: Oxygen Consumption (Vo2)contrasting

confidence: 61%

Effects of Motor-level Electrical Stimulations on Postprandial Glucose Levels in Non-Diabetic Young Individuals

Huang¹

2017

J Nov Physiother Phys Rehabil

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“…NMES is thought to preferentially recruit different motor units in position and in type. 25 Kimura et al 15 has argued the potential benefits in type 2 diabetes of a higher proportion of type IIb fibres being exercised. If a person both walks and uses this modality, then there will be a different fibre mix recruited by each exercise type and the total proportion of fibres exercised will be higher.…”

Section: Discussionmentioning

confidence: 99%

“… 1 Even traditional NMES techniques exercising at just two metabolic equivalents (oxygen consumption of 7 ml/kg/min) has been shown to enhance total body glucose uptake and attenuate postprandial hyperglycemia in the obese. 15 The therapeutic potential of traditional NMES on diabetes has been investigated previously with no improvement in haemoglobin A1c (HbA1c) or insulin sensitivity. 16 However, as a traditional NMES system was used, this had little physiological impact on study participants, for example, there was only a 9% increase in energy expenditure above baseline values.…”

Section: Introductionmentioning

confidence: 99%

Aerobic neuromuscular electrical stimulation—an emerging technology to improve haemoglobin A1c in type 2 diabetes mellitus: results of a pilot study

Crowe

Caulfield

2012

BMJ Open

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ObjectivesA new generation of neuromuscular electrical stimulation (NMES) devices can exercise aerobically at equivalent rates to voluntary exercise. Many with type 2 diabetes cannot or will not exercise sufficiently. The objective of this pilot investigation was to see (1) if it was an acceptable training modality for men with type 2 diabetes mellitus and (2) to assess effects on haemoglobin A1c levels.Design, setting, participants and interventionA case series of eight men with type 2 diabetes mellitus (aged 53±8; body mass index 32±5 5 kg/m2) trained with the NMES system for 1 h 6 times weekly for 8 weeks, unsupervised, at home. There were no other medication or lifestyle interventions. The aerobic NMES exercise system delivers a repeating set of four complex staggered pulses at high intensities (typically 100 mA+) through an array of eight thigh electrodes.Outcome measuresThe primary outcome measures were changes in haemoglobin A1c and the responses in a questionnaire on participants' perceptions of the system. Body mass and composition were also measured before and after the NMES intervention period.ResultsAll participants could use the system at a level that left them breathless and sweaty and with a heart rate over 120 beats per minute. Haemoglobin A1c levels improved by 0.8±0.7% from 7.4±1.3% (mean ± SD) to 6.6±1.0% (p=0.01). All participants considered the system suitable for people with diabetes, would recommend it and would continue to use it twice a week ‘to maintain improvements’.ConclusionsThese results suggest that aerobic NMES may be acceptable and have a beneficial effect on haemoglobin A1c of some men with diabetes. The treatment may be of particular benefit in those who will not or cannot do adequate amounts of voluntary exercise. A randomised control trial is required for conclusive efficacy data.

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“…Thus, standard exercise regimes are insufficiently appealing to the many who could but do not regularly exercise (Varo et al 2003) and the present NMES protocol could be an alternative. Moreover, it has recently been shown that an NMES protocol may also attenuate postprandial hyperglycemia in obese male participants (Kimura et al 2010). Thus NMES techniques may emerge as a potential alternative exercise method for overweight participants and people with diabetes.…”

Section: Discussionmentioning

confidence: 99%

Comparative effect of a 1 h session of electrical muscle stimulation and walking activity on energy expenditure and substrate oxidation in obese subjects

Grosset

Crowe

Vito

et al. 2013

Appl. Physiol. Nutr. Metab.

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It has previously been shown that low-frequency neuromuscular electrical stimulation (NMES) techniques can induce increases in energy expenditure similar to those associated with exercise. This study investigated the metabolic and cardiovascular effects of a 1 h session of lower limb NMES and compared cardiovascular response with that observed during walking in nine obese subjects (three males) (age = 43.8 ± 3.0 years; body mass index (BMI) = 41.5 ± 1.8 kg/m 2 ). The NMES protocol consisted of delivering a complex pulse pattern to the thigh muscles for 1 h. The walking test consisted of five 4-min bouts starting at 2 km/h with 1 km/h increments up to 6 km/h. In both tests, an open-circuit gas analyser was used to assess O 2 consumption (V O 2 ), CO 2 production (V CO 2 ), respiratory exchange ratio (RER), and heart rate (HR). Rates of fat oxidation (RFO) and carbohydrate oxidation (CHO) were estimated by indirect calorimetry. One hour of NMES significantly increased V O 2 , HR, RER, and mean energy expenditure compared with resting values, reaching 8.7 ± 1.3 mL·min −2 ·kg −1 (47% of V O 2peak ), 114.8 ± 7.5 bpm, 0.95, and 318.5 ± 64.3 kcal/h, respectively. CHO, but not RFO, increased during 1 h of NMES. With NMES, CHO was greater and RFO was less than at all walking speeds except 6 km/h. Lactate also increased more with NMES, to 3.5 ± 0.7 mmol versus a maximum of 1.5 ± 0.3 mmol with the walking protocol. These results suggest that NMES can be used in an obese population to induce an effective cardiovascular exercise response. In fact, the observed increase in energy expenditure induced by 1 h of NMES is clinically important and comparable with that recommended in weight management programs.Key words: obesity, neuromuscular electrical stimulation, oxygen consumption, energy expenditure, substrate oxidation. Mots-clés : obésité, stimulation électrique neuromusculaire, consommation d'oxygène, dépense énergétique, oxydation des substrats.

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Percutaneous Electrical Muscle Stimulation Attenuates Postprandial Hyperglycemia in Obese and Pre-obese Japanese Men

Cited by 11 publications

References 11 publications

Effects of Motor-level Electrical Stimulations on Postprandial Glucose Levels in Non-Diabetic Young Individuals

Effects of Motor-level Electrical Stimulations on Postprandial Glucose Levels in Non-Diabetic Young Individuals

Aerobic neuromuscular electrical stimulation—an emerging technology to improve haemoglobin A1c in type 2 diabetes mellitus: results of a pilot study

Comparative effect of a 1 h session of electrical muscle stimulation and walking activity on energy expenditure and substrate oxidation in obese subjects

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