Genetic syndromes such as Brugada syndrome can lead to lethal
ventricular arrhythmias. Cardiac Sympathetic Denervation has been shown
to be effective in ameliorating refractory ventricular arrhythmias. We
present a 33-year-old black female with a past medical history of
Brugada syndrome with an implantable cardiac defibrillator (ICD), who
presented with refractory ventricular tachycardia/atrial fibrillation
leading to cardiogenic shock, requiring Extracorporeal membrane
oxygenation (ECMO). The patient subsequently underwent bilateral
stellate ganglion sympathetic denervation in the setting of refractory
ventricular arrhythmias. We present this case report to showcase that
thoracoscopic bilateral cardiac sympathetic denervation can be an
effective definitive treatment option for ventricular arrhythmias
refractory to medical management.