Percutaneous Fully Endoscopic İnterlaminar Approach to the Filum Terminale: A Cadaveric Study

Yörükoğlu, Ali Güven; Tahta, Alican; Akçakaya, Mehmet; Sabancı, Pulat Akın; Aras, Yavuz; Aydöseli, Aydın; Dolgun, Müge; Sencer, Altay; Hepgül, Kemal

doi:10.1016/j.wneu.2016.05.055

Cited by 4 publications

(3 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cutting the FTI, removal of arachnoid bands and attachments, and release of the spinal cord is the main treatment strategy for TCS. This may be performed through the same surgical incision if the TCS is secondary to open spinal dysraphism, or via an endoscopic approach which provides a smaller skin incision, narrow durotomy, and minimal tissue damage [9,11]. Isolated transection of the FTE via an extradural approach for a patient with TCS has no significant effect on the release of the spinal cord [28].…”

Section: Discussionmentioning

confidence: 99%

“…This syndrome is often seen in children, and both the diagnosis and treatment are controversial and can be difficult for neurosurgeons. Cutting of the FT and release of the spinal cord is the main strategy of surgical treatment for TCS [9,10,11]. This procedure can be performed either by open surgery or an endoscopic approach [9,11].…”

Section: Introductionmentioning

confidence: 99%

“…Cutting of the FT and release of the spinal cord is the main strategy of surgical treatment for TCS [9,10,11]. This procedure can be performed either by open surgery or an endoscopic approach [9,11]. However, section of the FT may not provide any improvement in the urological outcome of patients with occult TCS [10].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Expression of Sigma-Class Glutathione-S-Transferase in Fetal and Pediatric Filum Terminale Samples: A Comparative Study

et al. 2019

View full text Add to dashboard Cite

Background and objectives: The pathophysiology of tethered cord syndrome (TCS) in children is not well elucidated. An inelastic filum terminale (FT) is the main factor underlying the stretching of the spinal cord in TCS. Our study aimed to investigate the expression of glutathione-S-transferase (GST) in children and fetal FT samples in order to understand the relationship between this enzyme expression and the development of TCS. Materials and Methods: FT samples were obtained from ten children with TCS (Group 1) and histological and immunohistochemical examinations were performed. For comparison, FT samples from fifteen normal human fetuses (Group 2) were also analyzed using the same techniques. Statistical comparison was made using a Chi-square test. Results: Positive GST-sigma expression was detected in eight (80%) of 10 samples in Group 1. The positive GST-sigma expression was less frequent in nine (60%) of 15 samples from Group 2. No statistically significant difference was detected between the two groups (p = 0.197). Conclusions: Decreased FT elasticity in TCS may be associated with increased GST expression in FT. More prospective studies are needed to clarify the mechanism of the GST–TCS relationship in children.

show abstract

Section: Discussionmentioning

confidence: 99%