Percutaneous Intraductal Radiofrequency Ablation is a Safe Treatment for Malignant Biliary Obstruction: Feasibility and Early Results

Mizandari, Malkhaz; Pai, Madhava; Xu, Feng; Válek, Vlastimil; Andrasina, Tomas; Quaretti, Pietro; Golfieri, Rita; Mosconi, Cristina; Ao, Guokun; Kyriakides, Constantinos; Dickinson, Robert; Nicholls, Joanna P.; Habib, Nagy

doi:10.1007/s00270-012-0529-3

Cited by 61 publications

(46 citation statements)

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“…RFA has been widely used in the ablation of esophagus dysplasia [8], rectum cancer [9], and liver carcinoma [10]. As for intraluminal radiofrequency ablation, there is limited clinical experience and a small quantity of reports [2][3][4].…”

Section: Discussionmentioning

confidence: 99%

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Percutaneous Intraluminal Radiofrequency Ablation for Malignant Extrahepatic Biliary Obstruction: A Safe and Feasible Method

Liu

et al. 2015

Dig Dis Sci

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Section: Discussionmentioning

confidence: 99%

“…Several studies have looked into the feasibility and safety of this procedure [2][3][4]. The present study retrospectively analyzed 47 patients who underwent 65 consecutive percutaneous intraluminal RFA combined with biliary stenting for the treatment of extrahepatic obstructive jaundice between September 2011 and May 2014.…”

Section: Introductionmentioning

confidence: 99%

Percutaneous Intraluminal Radiofrequency Ablation for Malignant Extrahepatic Biliary Obstruction: A Safe and Feasible Method

Liu

et al. 2015

Dig Dis Sci

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“…There have been reports of the use of intraductal RFA for the treatment of unresectable malignant biliary obstructions with percutaneous and endoscopic approaches, demonstrating its feasibility and safety; pain, cholangitis and asymptomatic biochemical pancreatitis have been reported as the only common complications (2,6,13), while hepatic coma, newly diagnosed left bundle branch block and partial liver infarction have been reported as uncommon complications (2,14,15). However, a few cases of hemobilia and mortality following intrabiliary RFA have also been reported (15).…”

Section: A B C D F E Discussionmentioning

confidence: 99%

Biliary tract perforation following percutaneous endobiliary radiofrequency ablation: A report of two cases

et al. 2016

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Abstract. Endobiliary radiofrequency ablation (RFA) has recently been recognized as a beneficial treatment option for malignant biliary obstruction using percutaneous or endoscopic approaches. The feasibility and safety of this method has been demonstrated in clinical studies, with pain, cholangitis and asymptomatic biochemical pancreatitis reported as relatively common complications. By contrast, hepatic coma, newly diagnosed left bundle branch block and partial liver infarction have been reported as uncommon complications. Biliary tract perforation is a serious potential complication of percutaneous intraductal RFA, which may result in severe infection, peritonitis or even mortality, and which has not been previously reported in clinical research. The current study presents the first reports of biliary tract perforation in two patients with unresectable malignant biliary obstruction following percutaneous intraductal RFA. Although the patient in case 1 succumbed 12 days after RFA, the minor biliary tract perforation in case 2 was successfully treated by the deployment of a self-expanding metal stent. This study demonstrates that biliary tract perforation should be recognized as a serious potential complication of endobiliary RFA, and that metal stent deployment should be considered as a treatment option for minor biliary tract perforation.

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“…et al 46 indicated that percutaneous intraductal radiofrequency ablation combined with biliary stenting was feasible and safe for malignant biliary obstruction including cholangiocarcinoma.…”

Section: 44mentioning

confidence: 99%

Multiple metallic stents placement for malignant hilar biliary obstruction: Perspective of a radiologist

Sato

Inaba

Hara

et al. 2016

Int J Gastrointest Interv

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A B S T R A C TIn the palliative setting, the necessity of biliary drainage of both liver lobes for malignant hilar biliary obstruction remains controversial. However, bilateral biliary drainage is a reasonable option to prevent cholangitis of the undrained lobe and to preserve liver function during the course of chemotherapy. Bilateral biliary drainage can be accomplished by the percutaneous or endoscopic placement of multiple self-expandable metallic stents (SEMS). Although SEMS placement via bilateral (multiple) percutaneous routes is technically simple, multiple percutaneous transhepatic biliary drainage (PTBD) may lead to additional morbidity. SEMS placement via a single percutaneous route is a useful method; however, negotiation of a guidewire into the contralateral bile duct is occasionally impossible if the hilar angle between the right hepatic duct and left hepatic duct is acute. Percutaneous dual SEMS placement is generally performed using the stent-in-stent technique (T configuration or Y configuration) or the side-byside technique. In addition, the crisscross technique has been reported as being a useful method for trisegmental drainage. The side-to-end technique is also useful for multiple SEMS placement. In the future, the combination of percutaneous intervention and endoscopic ultrasonography-guided procedures may be effective in the management of malignant hilar biliary obstruction.

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Percutaneous Intraductal Radiofrequency Ablation is a Safe Treatment for Malignant Biliary Obstruction: Feasibility and Early Results

Abstract: In this group of patients, it appears that this new approach is feasible and safe. Efficacy remains to be proven in future, randomized, prospective studies.

Cited by 61 publications

References 10 publications

Percutaneous Intraluminal Radiofrequency Ablation for Malignant Extrahepatic Biliary Obstruction: A Safe and Feasible Method

Percutaneous Intraluminal Radiofrequency Ablation for Malignant Extrahepatic Biliary Obstruction: A Safe and Feasible Method

Biliary tract perforation following percutaneous endobiliary radiofrequency ablation: A report of two cases

Multiple metallic stents placement for malignant hilar biliary obstruction: Perspective of a radiologist

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