Percutaneous intramedullary rod interchange in osteogenesis imperfecta

Middleton, R. W. D.; Frost, Richard

doi:10.1302/0301-620x.69b3.3294840

Cited by 9 publications

(4 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While tibial nailing has been performed in numerous prior rabbit studies, there does not appear to be a model that used interlocking screws. 19,20,[23][24][25][26][27][28] The current study provides one method to insert and interlock a nail that is fatigue resistant for the given loading protocol. The pre-and post-fatigue test limb strain of the current model are similar to McDuffee et al, 47 who report interfragmentary strains for an interlocked tibial nail in an equine ex vivo model; they did not provide data for intact bones as a control.…”

Section: Discussionmentioning

confidence: 99%

“…21,22 While an interlocked rabbit tibial nail does not appear to be available, a number of studies have inserted non-locked stainless steel or Cobalt-Chrome nails (a K wire or similar) into the rabbit tibia. 19,20,[23][24][25][26][27][28] Owing to the torsional instability common to this model, several groups have proposed the use of multiple K wires to lend a degree of torsional stability via an interference fit. 23,29 Regardless, the above models have not been used to study segmental loss, perhaps owing to the lack of positive interlocking of the bone-to-nail.…”

Section: Introductonmentioning

confidence: 99%

See 1 more Smart Citation

Development of an interlocked nail for segmental defects in the rabbit tibia

LeCronier

Papakonstantinou

Gheevarughese

et al. 2012

Proc Inst Mech Eng H

View full text Add to dashboard Cite

Previous animal models have been developed to study intramedullary nailing for challenging segmental defects in the tibia. In large animals, interlocked nail fixation created a stable environment suitable to study new bone growth technologies placed in the defect. To our knowledge, there are no comparable interlocked tibial defect models for the rabbit in which new technologies could be evaluated. Such a model would be helpful since the rabbit is a popular initial model for orthopedic research studies owing to its wide availability and low cost. While numerous studies have nailed the rabbit tibia, all were non-locked implants that allowed some degree of instability between the fracture fragments. In addition, the non-locked nails were constructed of stainless steel, whereas human nails are increasingly made from titanium alloy. In the current study, an interlocked titanium nail was developed for the rabbit tibia. It was implanted in cadaver tibiae and subjected to fatigue cycling in combined compression and bending at physiologic levels to 21,061 cycles. This duration is estimated to represent 12 weeks of gait by the animal. Before and after fatigue cycling, monotonic testing was performed in compression and bending at physiologic levels. The intact contralateral limbs served as controls. All limbs completed the cycling; the instrumented limbs exhibited interfragmentary cyclic strain amplitudes during fatigue (616 +/- 139 micro-strain), which was significantly greater than the control limbs (136 +/- 35 microstrain). Monotonic strain amplitudes for the test limbs in bending and compression were 4839 +/- 1028 and 542 +/- 122 microstrain, respectively; corresponding values for the control bones were 407 +/- 118 and 95 +/- 38 microstrain, respectively. These data are similar to those presented in prior studies in larger bone models. The current study presents one method for interlocked nail fixation for this complex tibial shaft fracture in a small animal.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductonmentioning

confidence: 99%

Development of an interlocked nail for segmental defects in the rabbit tibia

LeCronier

Papakonstantinou

Gheevarughese

et al. 2012

Proc Inst Mech Eng H

View full text Add to dashboard Cite

show abstract

“…The useful life of the solid rods has been found to average 2.5 years, and of the extendable rod, 4.1 years [4]. Middleton and Frost [5] have reported percutaneous intramedullary rod interchange in osteogenesis imperfecta. This relatively atraumatic procedure may allow more frequent exchange of rods, lessening the likelihood of deformity and fracture of the unsupported skeleton when the bone has outgrown the intramedullary fixation.…”

Section: Discussionmentioning

confidence: 99%

Percutaneous nailing in the management of osteogenesis imperfecta

Sijbrandij¹

1990

International Orthopaedics

View full text Add to dashboard Cite

Marked deformities of the skeleton may develop in the severe form of osteogenesis imperfecta. Internal fixation can be effective in the treatment and prevention of fractures and deformities. Eight years ago, axial correction of deformities of the femora and tibiae by manual osteoclasis was carried out in a 7 year old girl in whom osteogenesis imperfecta had produced severe bowing of the long bones of the legs. Internal metal splints were introduced percutaneously to lie partially in, and partially alongside, the bone, to obtain fixation in the correct position. This treatment resulted in the prevention of refracture of the legs, while correction was maintained.

show abstract

“…Sofield and Millar described a method of treatment of deformities with multiple osteotomies and intramedullary rods in children with OI, 4 and surgical interventions have progressed with the development of telescoping rods, 5 less invasive methods 6,7 and additional modified techniques. Sofield and Millar described a method of treatment of deformities with multiple osteotomies and intramedullary rods in children with OI, 4 and surgical interventions have progressed with the development of telescoping rods, 5 less invasive methods 6,7 and additional modified techniques.…”

Section: Introductionmentioning

confidence: 99%