Percutaneous Liver Biopsies: Safety and Efficacy

Sezgın, Orhan; Altıntaş, Engin; Üçbilek, Enver; Tombak, Anıl

doi:10.5336/medsci.2009-13508

Cited by 9 publications

(9 citation statements)

References 13 publications

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“…In our study, the rates of diagnosis with 16G and 18G needles were 90.7% and 83.3%, respectively, and no statistically significant difference was found between the needles in terms of establishing the diagnosis. However, our rate of diagnosis was lower compared to that in studies in the literature (25,32).…”

Section: Discussioncontrasting

confidence: 83%

A Comparison of Needle Types and Biopsy Techniques Used in Liver Biopsies of Chronic Hepatitis B Patients

Karavaş¹,

Karakeçili²,

Balcı³

2019

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Objectives: To investigate the effect of the biopsy technique used in percutaneous liver biopsies applied with semi-automatic 16 gauge (G) and 18G Tru-cut and Menghini aspiration needles in patients with chronic hepatitis B (CHB) on pathological evaluation. Materials and Methods: The study included 104 cases diagnosed with CHB who underwent liver biopsy between 2013 and 2018. The pathology results of biopsies were evaluated with the Menghini technique under ultrasound (USG) guidance (n=26), and with 16G (n=54) and 18G (n=24) semi-automatic Tru-cut needles under USG. Results: The fibrosis score in 5 (9.3%) of the 16G cases and in 3 (12.5%) of the 18G cases, and the ISHAK score in 3 (5.6%) of the 16G and in 1 (4.2%) of the 18G cases could not be determined. There was no significant difference between the methods and needle types in terms of the number of pieces, number of portal sites, fibrosis and ISHAK score (p>0.05). There was a statistically significant difference between the biopsies performed with Menghini method and Tru-cut method with 16G and 18G (p<0.0001) in terms of material length. The diagnosis rates for the Menghini technique, and 16G and 18G Tru-cut needles were 100%, 90.7% and 83.3%, respectively, with no statistically significant difference determined (p>0.05). Conclusion: Although a larger tissue piece is obtained with the Menghini technique, allowing evaluation of a larger portal area, no significant difference was determined between the techniques in the pathological evaluation. Taking patient safety and comfort into consideration, Tru-cut needle biopsy under USG guidance is recommended rather than the Menghini technique as less trauma is created.

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Section: Discussioncontrasting

confidence: 83%

A Comparison of Needle Types and Biopsy Techniques Used in Liver Biopsies of Chronic Hepatitis B Patients

Karavaş¹,

Karakeçili²,

Balcı³

2019

vhd

View full text Add to dashboard Cite

show abstract

“…In our study, rates of diagnosis with 16G and 18G needles were 90.7% and 83.3%, respectively, and no statistically significant difference was found between the needles in terms of establishing the diagnosis. However, our rate of diagnosis was lower compared to the studies in the literature (25,32).…”

Section: Discussioncontrasting

confidence: 79%

A Comparison of Needle Types and Biopsy Techniques used in Liver Biopsies of Chronic Hepatitis B Patients

Karavaş¹,

KARAKEÇİLİ²,

Balcı³

2019

vhd

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Objectives: To investigate the effect on pathological evaluation of the biopsy technique used in percutaneous liver biopsies applied with semi-automatic 16 gauge (G) and 18G Tru-cut and Menghini aspiration needles in patients with chronic hepatitis B(CHB). Materials and Methods: The study included 104 cases diagnosed with CHB applied with liver biopsy between 2013-2018. The pathology results of biopsies were evaluated with the Menghini technique under ultrasound(USG) guidance (n:26), and with 16G (n:54) and 18G (n:24) semi-automatic Tru-cut needles under USG. Results: The fibrosis score in 5 (9.3%) of the 16G cases and in 3 (12.5%) of the 18G cases, and the ISHAK score in 3 (5.6%) of the 16G and in 1 (4.2%) of the 18G cases could not be determined. There was no significant difference between the methods and needle types in terms of the number of pieces, number of portal sites, fibrosis and ISHAK score(p>0.05). There was a statistically significant difference between the biopsies performed with Menghini method and tru-cut method with 16G and 18G(p<0.0001) in terms of material length. The diagnosis rates for the Menghini technique, and 16G and 18G Tru-cut needles were 100%, 90.7% and 83.3%, respectively, with no statistically significant difference determined (p>0.05). Conclusion: Although a larger tissue piece is obtained with the Menghini technique, allowing evaluation of a larger portal area, no significant difference was determined between the techniques in the pathological evaluation. Taking patient safety and comfort into consideration, Tru-cut needle biopsy under USG guidance is recommended rather than the Menghini technique as less trauma is created.

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“…However, attempts to increase safety and decrease complications of liver biopsy should be made (2, 5). There is also a statistically significant decrease in the complication rates of liver biopsies when performed under ultrasound guidance (4, 6, 11, 12).…”

Section: Introductionmentioning

confidence: 99%

Percutaneous Liver Biopsies Guided with Ultrasonography: A Case Series

et al. 2013

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BackgroundAlthough liver biopsy is an easy procedure for hospitalized patients and outpatients, some complications may occur.ObjectivesTo evaluate the efficiency, complications, safety and clinicopathological utility of ultrasonographic-guided percutaneous liver biopsy in diffuse liver disease.Patients and MethodsIn our retrospective study, we evaluated ultrasound-assisted needle biopsies that were performed in outpatients from October 2006 to July 2010. The liver biopsies were performed following one-night fasting using the tru-cut biopsy gun (18-20 gauge) after marking the best seen and hypovascular part of the liver, distant enough from the adjacent organs.ResultsA total of 1018 patients were referred to our radiology department. Most of the patients had hepatitis B (60.6%). The biopsy specimens were recorded and sent to our pathology department for histopathological examination.ConclusionAccording to the results of our series, percutaneous liver biopsy using the tru-cut biopsy gun guided by ultrasonography can be performed safely. We resolve that routine ultrasound of the puncture site is a quick, effective and safe procedure. The complication rate is very low. The US-assisted percutaneous liver biopsy should be used for all cases.

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Percutaneous Liver Biopsies: Safety and Efficacy

Cited by 9 publications

References 13 publications

A Comparison of Needle Types and Biopsy Techniques Used in Liver Biopsies of Chronic Hepatitis B Patients

A Comparison of Needle Types and Biopsy Techniques Used in Liver Biopsies of Chronic Hepatitis B Patients

A Comparison of Needle Types and Biopsy Techniques used in Liver Biopsies of Chronic Hepatitis B Patients

Percutaneous Liver Biopsies Guided with Ultrasonography: A Case Series

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