Percutaneous nerve field stimulation (PENS) of the occipital region as a possible predictor for occipital nerve stimulation (ONS) responsiveness in refractory headache disorders? A feasibility study

Abstract

Presurgical applied occipital PENS failed to identify ONS responders sufficiently according to our study protocol, thus requiring further specific investigations to determine its predictive usefulness.

Clinical Effect of C2 Peripheral Nerve Field Stimulation Using Electroacupuncture for Primary Headache

“…Therefore EA‐C2‐PNfS may function via the same mechanism as surgical PNfS. However, the voltage of our EA‐C2‐PNfS was lower than those in previously reported ONS studied .…”

Burst Spinal Cord Stimulation Increases Peripheral Antineuroinflammatory Interleukin 10 Levels in Failed Back Surgery Syndrome Patients With Predominant Back Pain

“…Special consideration of specific biofluid compartments (CSF, blood) would appear to be most important, as the patterns of expression for neuroinflammatory mediators appear to differ based on the compartment remains an experimental approach. Characterization of clinical phenotypes revealed a positive predictive value for co-incidental depressive symptoms prior to neuromodulation, while anxiety and cognitive decline were found to be a negative predictor related to tonic SCS responsiveness (32)(33)(34)(35)(36)(37).…”

Chronic Headache and Neuromodulation

“…As ONS only covers 85% of the head leaving the forehead uncovered, some have combined it with SONS [15,89,90]. Percutaneous ONS is recommended to foresee the results of a permanent implantation [91]. In any case, a temporary external stimulation must be performed before definitive implantation [35].…”