“…Although a clear cut-off point for the vegetation size has not been defined, many physicians would advocate surgical removal of leads of infected leads with large vegetations (>1-1,5 cm) [32], [33]. More recent evidence, however, suggests that even larger vegetations can be safely removed percutaneously [21]. Laboratory examinations should include: blood typing and crossmatch, a full blood count, coagulation profile, electrolytes, renal and liver function tests, virology screen (Hep B, C and HIV), Creactive protein and erythrocyte sedimentation rate.…”