Percutaneous renal cyst aspiration and treatment with alcohol

Abstract

Twenty-two simple renal cysts of 16 patients were aspirated under guidance of ultrasound, with a 20-gauge needle with stylet. Sixteen of those cysts were treated with 96% alcohol. All cysts that were not treated with alcohol recurred within 10 weeks. Treatment with alcohol revealed no recurrences in 3 months follow-up for 12 patients and 6 months follow-up for 4 patients. No major complications were encountered.

Percutaneous Ethanol Injection of the Prostate as Minimally Invasive Treatment for Benign Prostatic Hyperplasia: Preliminary Report

“…The possible role of coagulative necrosis after percutaneous ethanol injection therapy has been investigated in a variety of diseases. Percutaneous ethanol injection therapy is currently a steadily growing therapeutic method that is widely used in the ablation of solid and cystic masses (hyperparathyroidism, hepatic cysts and carcinomas [7, 8]). Local infiltration of pure ethanol has been demonstrated to lead to cell death by causing cell membrane lysis, protein denaturation and vascular occlusion resulting in a coagulative necrosis of tissue.…”

The ole of Choice-Lck Catheter and Trocar Technique in Percutaneous Ablation of Symptomatic Renal Cysts

“…In aspiration alone, the destruction of epithelial cell lining will not happen and the epithelial cells will continue secreting fluid cyst. In other words the cyst fluid re-accumulates (4). Secretory epithelial lining the cyst wall must be destructed in order to prevent recurrence.…”

“…In this way, destruction of cysts occur without affecting the renal parenchyma. Ethanol as a sclerosing agent has been mentioned in the literature, and there are studies that have reported success rates of over 90% (1, 2, 4). Akinci and colleagues treated 98 simple renal cysts with percutaneous ethanol sclerotherapy with a single session technique (2).…”

“…Our success rate was similar to other studies. In the study conducted by Ozgur et al (4), a number of patients developed recurrence during follow-up while a sclerosing agent was not used for any of them. In our study, no recurrence or increase in the cyst volume was reported during follow-up.…”

“…The indication for treatment is based on urinary tract obstruction. Several methods for treatment of the cyst including surgical and percutaneous procedures have been proposed; namely, percutaneous marsupialization (3), percutaneous aspiration (4), and open and laparoscopic cyst unroofing (5). Aspiration alone without injection of a sclerosing agent has been reported with a higher recurrence rate.…”