Repetitive strain injury (RSI) is considered a nonspecific neck, shoulder, elbow, forearm, wrist, and/or hand-related overuse pain syndrome caused by sustained low-level static and/or repetitive muscle activity. This type of prolonged, low-intensity, and repetitive muscle activity induces local changes in skeletal muscle morphology and circulation, such as changes in the amount and distribution of muscle type I and IIA fibers, 13,[17][18][19][20] These local changes have been found in muscles affected by RSI and are believed to contribute to the clinical presentation of RSI complaints. Interestingly, RSI is also related to systemic problems such as reduced function of small and large sensory and sympathetic fibers.9 Moreover, a lower skin temperature was found in both arms of patients with unilateral RSI, which may be related to an underlying systemic change in the regulation of skin blood flow. 6,7,26 Nonetheless, previous studies have typically examined muscular or vascular adaptations of the affected side only.Recently, we found lower muscle oxygen consumption in forearm muscles affected by RSI.2 Whether changes in oxygen consumption are also present in the nonaffected arm of patients with unilateral RSI has not been investigated and may have important clinical implications. To date, treatment of RSI has often focused on local complaints only; however, if systemic changes are present in patients with RSI, optimal treatment may require a more systemic approach. For example, whole-body exercise training has well-established beneficial and systemic effects on the vasculature.
8,27T T STUDY DESIGN: Case-control study.
T T OBJECTIVES:To investigate whether oxygen consumption and blood flow at rest and after exercise are lower in the affected arm of patients with repetitive strain injury (RSI) compared to controls, and lower in the healthy nonaffected forearm within patients with unilateral RSI.
T T BACKGROUND:RSI is considered an upper extremity overuse injury. Despite the local presentation of complaints, RSI may be represented by systemic adaptations. Insight into the pathophysiology of RSI is important to better understand the development of RSI complaints and to develop effective treatment and prevention strategies.
T T METHODS: Twenty patients with unilateralRSI and 20 gender-matched control subjects participated in this study. Forearm muscle blood flow and oxygen consumption were measured using near-infrared spectroscopy at baseline and immediately after isometric handgrip exercises at 10%, 20%, and 40% of the individual maximal voluntary contraction.
T T RESULTS:Unilateral RSI resulted in a lower oxygen consumption and blood flow in the affected forearm at baseline and lower oxygen consumption after incremental handgrip exercises compared to controls (P<.05). In addition, exercise-induced blood flow and oxygen consumption in the nonaffected forearm in patients with RSI were similarly reduced.
T T CONCLUSION:Blood flow and oxygen consumption after exercise are similarly attenuated in the affected and nonaff...