Perfil epidemiológico e fatores prognósticos no tratamento cirúrgico do adenocarcinoma de próstata clinicamente localizado

Nassif, Aissar Eduardo; Filho, Renato Tambara; Paula, Regina Xavier Gomes de; Taguchi, Willian Setsumi; Pozzobon, Hélio Jorge

doi:10.1590/s0100-69912009000400010

Cited by 6 publications

(6 citation statements)

References 38 publications

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“…The mean age, race, and preoperative PSA level of our patients were in agreement with those reported in previous studies. 1 4 14 The TNM tumor stage was in agreement with that of a recent study by Nassif et al (65% of patients were pT2c); however, the average tumor stage of patients in this study was different from that of recent international reports. 14 For instance, a study on 369 patients by Freedland et al in the United States reported that the predominant TNM tumor stage was pT2a (34% of patients).…”

Section: Discussionsupporting

confidence: 90%

“… 1 4 14 The TNM tumor stage was in agreement with that of a recent study by Nassif et al (65% of patients were pT2c); however, the average tumor stage of patients in this study was different from that of recent international reports. 14 For instance, a study on 369 patients by Freedland et al in the United States reported that the predominant TNM tumor stage was pT2a (34% of patients). 9 Another study performed in United States by Makarov et al reported the predominant stage of 5730 patients as pT1c (77% of patients).…”

Section: Discussionsupporting

confidence: 90%

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Gleason score and tumor laterality in radical prostatectomy and transrectal ultrasound-guided biopsy of the prostate: a comparative study

et al. 2015

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We aimed to compare Gleason score and tumor laterality between transrectal ultrasound-guided biopsy of the prostate (TRUSBX) and radical prostatectomy (RP). Some factors that could cause a discrepancy in results between these two procedures were also evaluated. Among the 318 cases reviewed, 191 cases were selected for inclusion in this comparative study. We divided the patients into two groups using the Gleason score: an intermediate/high-grade group (≥7) and a low-grade group (<6). Exploratory analyses were conducted for comparisons between groups. We also performed comparisons between TRUSBX and RP for tumor laterality. TRUSBX overestimated 6% and underestimated 24% cases in comparison with RP for Gleason score, and overestimated 2.6% and underestimated 46% cases compared with RP for tumor laterality. Biopsy specimens were slightly smaller in TRUSBX cases with underestimated tumor laterality (P < 0.05), and no relationship between the biopsy specimen size and underestimated Gleason score in TRUSBX was found. Prostatic volume showed no statistical correlation with the likelihood of under or overestimation (P > 0.05). Thus, our study showed that TRUSBX has a high likelihood of underestimating both the Gleason score and tumor laterality in prostate cancer (PCa). The size of the fragment appears to be an important factor influencing the likelihood of laterality underestimation and Gleason score overestimation via TRUSBX. Due to the high likelihood of underestimation of the Gleason score and tumor laterality by 12-core prostate biopsy, we conclude that this type of biopsy should not be used alone to guide therapy in PCa.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 90%

Gleason score and tumor laterality in radical prostatectomy and transrectal ultrasound-guided biopsy of the prostate: a comparative study

et al. 2015

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“…Um estudo realizado por Nassif (2009) [26] demonstrou que a maior incidência de desenvolvimento da doença é na sexta década de vida, oscilando na faixa etária de 50 -79 anos, apontando a idade como um dos fatores determinantes para o desenvolvimento do câncer de próstata. Dessa forma, nossos dados corroboram com os achados de outros autores em que a faixa etária mais acometida pela neoplasia compreende idades entre 60 -79 anos.…”

Section: Discussionunclassified

Análise da ocorrência de neoplasias na microrregião de Vitória da Conquista, Bahia

Almeida¹,

Lima²,

Lacerda³

et al. 2016

Scientia Plena

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A incidência de neoplasias de mama, estômago e próstata têm aumentado consideravelmente no mundo, decorrente das mudanças no perfil de morbidade e mortalidade. Estudos acerca da ocorrência deste tipo de patologia fornecem informações sobre o perfil epidemiológico de determinada região, o que reflete diretamente a importância do estudo no controle e prevenção da doença, além do desenvolvimento de medidas para tratamento. Deste modo, o objetivo deste estudo foi analisar a ocorrência de neoplasias de mama, de próstata e de estômago, bem como caracterizar seu perfil histopatológico, na microrregião de Vitória da Conquista, Bahia. Foram analisados 3269 pacientes, correspondentes ao período de 2009 a 2013, disponibilizados pelo Laboratório de Anatomia Patológica e Citopatologia MICRO, através da aplicação de um questionário para análise de variáveis como gênero, idade, ano da biópsia, neoplasia diagnosticada e seu subtipo histológico. Dentre as neoplasias investigadas, próstata mostrou-se mais ocorrente, correspondendo a 70,5% dos laudos analisados. Seguido de mama, que apresentou como subtipo histológico mais frequente o carcinoma ductal infiltrante. O adenocarcinoma gástrico do tipo intestinal foi o tipo histológico predominante encontrado na coleta dentre as neoplasias do estômago. Deste modo, o estudo fornece uma base acerca do perfil de ocorrência das neoplasias na microrregião de Vitória da Conquista, indicando que estas seguem os padrões epidemiólogicos relatados anteriormente para outras regiões.Palavras-chave: neoplasias gástricas; neoplasias da próstata; carcinoma ductal.The incidence of breast cancer, stomach and prostate cancers have increased considerably in the world, resulting from changes in the morbidity and mortality profile. Studies on the occurrence of this type of pathology provide information on the epidemiological profile of a given region, which directly reflects the importance of studying the control and prevention of disease, and the development of measures for treatment. Thus, the aim of this study was to analyze the occurrence of breast, prostate and stomach cancers as well as your histological profile in the microregion of Vitória da Conquista, Bahia. To do so, 3269 patients were analyzed, for the period 2009-2013, provided by the Laboratory of Pathology and Cytopathology MICRO, by applying a questionnaire to analyze variables such as gender, age, year of biopsy and its histological subtype. Among the investigated cancer, prostate was more occurring, corresponding to 70.5% of the analyzed reports. Followed by breast neoplasias, who presented the most common histological subtype infiltrating ductal carcinoma. Gastric adenocarcinoma intestinal type was the predominant histologic type found in the collection among the cancers of the stomach. Thus, the study provides a basis about the occurrence profile of cancers in the microregion of Vitória da Conquista, indicating that they follow the previously reported epidemiological patterns to other regions.

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“…Considerando as características cirúrgicas, o escore (12,17) . Outros dois, apenas para o Gleason, sendo o estádio mais frequente o T1c (60% e 77%) (18)(19) .…”

Section: Muitos Tumores Clinicamente Classificadosunclassified

Qualidade de vida em pacientes submetidos à prostatectomia radical

Goluart

Miranzi

Goulart³

2014

Rev. Eletr. Enf.

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Perfil epidemiológico e fatores prognósticos no tratamento cirúrgico do adenocarcinoma de próstata clinicamente localizado

Cited by 6 publications

References 38 publications

Gleason score and tumor laterality in radical prostatectomy and transrectal ultrasound-guided biopsy of the prostate: a comparative study

Gleason score and tumor laterality in radical prostatectomy and transrectal ultrasound-guided biopsy of the prostate: a comparative study

Análise da ocorrência de neoplasias na microrregião de Vitória da Conquista, Bahia

Qualidade de vida em pacientes submetidos à prostatectomia radical

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