“…For example, lower-quadrant abdominal pain is a key feature of both AD and acute appendicitis, but some differences exist; for example, it has been reported that the pain associated with AD is milder and longer lasting than that associated with appendicitis, and AD tends to affect adults aged >30 years with a history of similar episodes [ 4 , 6 ], whereas appendicitis is more common in children. Most patients seek medical advice once the symptoms become more prominent, and the risk of perforation increases [ 6 ]. Generally, the risk of perforation of AD has been shown to be 3–4 times higher than that of acute appendicitis, and this is associated with a 30-fold higher mortality risk [ 1 , 3 , 7 ].…”