Perforating lichenoid reaction to amlodipine

Lakshmi, Chembolli; Srinivas, CR; Ramachandran, Bindu; Pillai, Suma B; Nirmala, V

doi:10.4103/0019-5154.41659

Cited by 5 publications

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most commonly implicated agents are nonsteroidal anti-inflammatory drugs and angiotensin-converting enzyme inhibitors. [ 22 23 24 ] Systemic medications like antimalarials[ 25 26 ] and antihypertensive drugs[ 27 28 ] are also implicated. Diuretics, oral hypoglycemic agents, gold salts, penicillamine, and beta blockers are also reportedly associated with development of OLLs.…”

Section: Methodsmentioning

confidence: 99%

Oral lichenoid lesions - A review and update

2015

View full text Add to dashboard Cite

Background:Oral lichenoid lesions or reactions (OLLs/OLRs) are clinical and histological contemporaries of the classical oral lichen planus (OLP) that have generated a lot of debate in literature. In contrast to the idiopathic nature of OLP, OLLs are often associated with a known identifiable inciting factor. A superficial examination of these lesions clinically and histologically often reveals many similarities with OLP, but recent data indicate that distinguishable features do exist and form the basis of most classifications.Aims and Objectives:This paper attempts to collate available data in English literature on OLLs, highlight distinguishing features clinically and histologically and reflect on the malignant transformation potential and treatment modalities of the condition.Materials and Methods:A comprehensive search of medical and dental databases including PubMed, Ovid, Cochrane, Pubget, Researchgate, and non-medical search engines were utilized for the review. The search words included “oral lichen planus”, “oral lichenoid lesions”, “oral drug reactions”, “lichenoid dysplasia”, and “adverse effects of dental materials”.Review Results:OLLs seem to grossly underrated and most cases were clubbed as OLP. Definite clinical and histological features were uncovered to establish the identity of this lesion. Associations with dental restorative materials, drugs, and medications have been conclusively proven in the etiology of this condition. Specific markers are being utilized to diagnose the condition and monitor its progress.Conclusion:Substantial differentiating features were uncovered to delineate OLLs as a separate entity with definite etiology, pathogenesis, and a high malignant transformation rate compared with OLP.

show abstract

Section: Methodsmentioning

confidence: 99%

Oral lichenoid lesions - A review and update

2015

View full text Add to dashboard Cite

show abstract

Calcium Channel Blockers

Özkaya

Yazganoğlu

2014

Adverse Cutaneous Drug Reactions to Cardiovascular Drugs

View full text Add to dashboard Cite

Oral and vulvo-vaginal lichenoid reactions due to mitotane (Lysodren)

Schmouchkovitch¹,

Herry²,

Thuillier

et al. 2017

Medicine

View full text Add to dashboard Cite

Background:The purpose of pharmacovigilance (drug safety) is collection, detection, assessment, monitoring, and prevention of adverse effects with pharmaceutical products. It is meant to identify, characterize, prevent, or minimize actual or potential risks relating to medicinal products. To prevent these adverse effects and improve our practice, health professionals have a duty to report side effects to assess this risk and evaluate the benefit/risk requirements. Mitotane (Lysodren) is used for treating adrenocortical carcinoma. Currently, no side effects concerning oral and genital mucosa have been reported.Case Summary:This case report is about a 50 years old woman. Six months after the initiation on mitotane treatment, she developed erosive lesions located on the oral and vaginal mucosa. These drug reactions were diagnosed as erosive lichen planus by the biopsy. This lichenoid lesions were resistant to the usual treatments, mitotane being at the time not replaceable.Conclusion:This case describes an unreported adverse effect of mitotane, it is – to our knowledge – the 1st description of erosive lichenoid drug reaction due to Mitotane.

show abstract

Perforating lichenoid reaction to amlodipine

Cited by 5 publications

References 4 publications

Oral lichenoid lesions - A review and update

Oral lichenoid lesions - A review and update

Calcium Channel Blockers

Oral and vulvo-vaginal lichenoid reactions due to mitotane (Lysodren)

Contact Info

Product

Resources

About