Perforations and haemorrhages after colonoscopy in 2010: A study based on comprehensive French health insurance data (SNIIRAM)

Post-Colonoscopy Complications: A Systematic Review, Time Trends, and Meta-Analysis of Population-Based Studies

“…Overall, the mean pooled colonoscopic completion rate was 93.1% (range 50.0-99.0%) ( 5,6,8,9,(11)(12)(13)15,16,21,24 ). In eight studies, colonoscopy was performed for symptoms, screening/surveillance, and therapeutic indications ( 6,7,12,(15)(16)(17)20,22 ). Two studies examined symptomatic and therapeutic colonoscopies ( 19,21 ), two symptomatic and screening/surveillance ( 9,13 ), fi ve only screening/surveillance ( 5,8,10,11,18 ), and four only therapeutic colonoscopy (populationbased studies of patients undergoing polypectomy) ( 4,14,24,25 ).…”

“…Fourteen studies were retrospective ( 4,7,8,(10)(11)(12)14,15,17,19,21,22,24,25 ) and seven were prospective studies ( 5,6,9,13,16,18,20 ). Th ere were four studies from the United States ( 5,12,17,22 ), three from Canada ( 15,20,21 ), ten from Europe (6)(7)(8)(9)(10)(11)13,16,18,19 ), three from South-Korea ( 14,24,25 ), and one from New Zealand ( 4 ). Mean age of the study populations varied from 50.4 to 70.0 years ( 4,6,10,14-21,24,25 ) (median age, 57 to 75 years ( 5,9,13,16,21 )); 51.5% were males (4)(5)(6)…”

“…Th ere were four studies from the United States ( 5,12,17,22 ), three from Canada ( 15,20,21 ), ten from Europe (6)(7)(8)(9)(10)(11)13,16,18,19 ), three from South-Korea ( 14,24,25 ), and one from New Zealand ( 4 ). Mean age of the study populations varied from 50.4 to 70.0 years ( 4,6,10,14-21,24,25 ) (median age, 57 to 75 years ( 5,9,13,16,21 )); 51.5% were males (4)(5)(6)(7)(8)(9)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)24,25 ). Overall, the mean pooled colonoscopic completion rate was 93.1% (range 50.0-99.0%) ( 5,6,8,9,…”

“…Post-colonoscopy "perforation" rate ranges from 0 to 1.7/1,000 colonoscopies (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23), post-colonoscopy "bleeding" rate from 0 to 22.3/1,000 colonoscopies ( 4-11,13-18, 20-22,24,25 ), and "mortality" rate from 0 to 2.0/1,000 colonoscopies (4)(5)(6)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)25 ). In screening populations, an overall postcolonoscopy complication rate of 2.8/1,000 procedures has been reported ( 26 ).…”

Endoscopic closure of iatrogenic perforation

“…30 Diagnostic colonoscopy had lower rate of perforation than colonoscopy with polypectomy (0.01% vs 0.1%) 30,31 and sigmoid colon was reported as the most common location for perforation. 31 Other factors that associated with perforation are polyp larger than 1 cm, numbers of polyp > 4, emergency colonoscopy, low volume colonoscopist, 30 or polyp at the cecum. 32 Colonic perforation during diagnostic colonoscopy is mostly caused by the scope and this injury seems to have a large colonic wall defect (mean size 19.3 mm).…”