Titanium alloys, such as Ti6Al4V, have become increasingly prevalent in aerospace and biomedical industries owing to their exceptional mechanical properties and corrosion resistance. However, the machining of these alloys presents significant challenges including high tool wear, poor surface finish, and low productivity. This study focused on enhancing the machinability of Ti6Al4V during CNC turning using the Taguchi optimization method. This approach aims to identify the optimal cutting parameters that minimize the surface roughness, flank wear, and crater wear, thereby improving the overall machining performance. This study systematically investigated the influence of various cutting parameters on machining outcomes. The experimental results demonstrate that the Taguchi method effectively determines the optimal process parameters, leading to a significant reduction in surface roughness and tool wear. These findings highlight the potential of the Taguchi optimization technique for achieving improved machinability and sustainability in the machining of Ti6Al4V.