In this study, two semi-active control algorithms are synthesised on the basis of the measured nonlinear force-velocity properties of a Magneto-Rheological (MR) damper, including the current-dependent hysteresis and post yield saturation. The control algorithms employ the well-known sky-hook control condition function, suspension travel limits and a modulation function to compensate for the switching discontinuities. The results show that the proposed semi-active control synthesis could help achieve improved shock isolation while retaining adequate control of continuous WBV. A Hardware-In-the-Loop (HIL) test and simulation platform are developed for tuning of the proposed semi-active controllers and validation of the analytical formulations.Reference to this paper should be made as follows: Ma, X.Q., Rakheja, S. and Su, C-Y. (2008) 'Synthesis of a semi-active suspension seat for attenuation of Whole-Body Vibration and shock', Int. J. Vehicle Design, Vol. 47, Nos. 1/2/3/4, pp.157-175. Biographical notes: Xiao Qing Ma received her MSc and PhD in Mechanical Engineering at Concordia University, Montreal, Canada, in 2001 and 2006.Her research covers vehicle vibration analyses and control, modelling and simulation for mechanical system, robotics and advanced manufacturing technologies, and non-linear or linear control system. She is currently a postdoctoral fellow in robotic mechanical system laboratory, centre for intelligent machines, in McGill University, Montreal, Canada.Subhash Rakheja obtained his BEng and PhD in Mechanical Engineering at Concordia University, Montreal, Canada. His research interests include advanced transportation systems and highway safety, human responses to workplace vibration and driver-vehicle interactions. His research work in this area has evolved to what is called vehicular ergodynamics, a field that involves systematic studies on the dynamics of the transport system coupled with the human operator, with a special emphasis on the dynamic interactions.Chun-Yi Su received his BE degree in Control Engineering from Xian University of Technology in 1982, his ME and PhD degrees in control 158 X.Q. Ma et al. where he is currently a Professor of Mechanical Engineering and holds the Concordia Research Chair in Control. His research covers control theory and its applications to various mechanical systems. His current main research interests are in control techniques for smart material based actuators, vehicle suspension and vibration, robotic and mechatronic systems, and fuzzy control for non-linear systems.