Studying the stability of power converters and improving the performance is a major concern for researchers in the domain of power electronics. In this context, the DC-DC Zeta converter is studied in this paper and the closed-loop operation is comprehensively investigated by employing swarm intelligence (SI) algorithms with a view to design an optimized proportional-integral (PI) controller. These algorithms have been increasingly used to develop and optimize power converters in recent years. The state-space averaging technique was used to design the converter’s closed-loop transfer function. Hence, the traditional and SI algorithm-based PI controllers are inspected, and comparative analysis is presented. Four objective functions termed as integral absolute error, integral time absolute error, integral square error, integral time squared error, gain values, and different performance parameters such as percentage of overshoot, rise time, settling time, and peak amplitude are tabulated to examine the stability of the system. Furthermore, eigenvalues have been analyzed for determining the stability of the system extensively. Finally, a detailed comparative study is shown to provide a detailed evaluation of the performances where ant colony optimization for continuous domains (ACOR)-based PI controller has shown promising results than other SI-based controllers in terms of percentage of overshoot (2.27%), rise time (1.54 μs), and settling time (0.103 μs). All the simulation results and analysis are obtained using the MATLAB-Simulink.