The large-scale system’s mission process and the interaction within the system are becoming more complex with the improvement of the integration and intelligence, and the complex interactions among multiple factors, such as the unsafe behavior of personnel, equipment failures, and environmental interference, make safety analysis a greater challenge. Aimed at the safety of carrier aircraft, an integrated system modeling and safety analysis method for aircraft landing process were proposed based on System Modeling Language (SysML) and Simulink. First, the SysML models were built according to the analysis of the mission process, including system structure and behavior process, using multiple diagrams. Second, the SysML models were transformed into and integrated with the Simulink platform to build entity models with continuous dynamic characteristics and to perform safety analysis through simulation. Finally, an example of aircraft attitude control during landing was given to demonstrate the proposed method, and the safety states were analyzed and assessed under different disturbance conditions.