Performance assessment of the NIRS-based medical system of evaluating therapeutic effect

Zhao, Ke; Li, Nanxi; Pan, Boan; Li, Ting

doi:10.1016/j.microrel.2018.06.017

Cited by 4 publications

(3 citation statements)

References 26 publications

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“…As the change in concentration becomes smaller, the step between two adjacent steps shrinks. Until the injection of 0.2 mL, the step of optical density (ΔOD) variation disappears and a relatively stable rising line is realized [ 24 ]. As seen from the experiments, the device can detect a 1% change in blood volume, demonstrating a high level of sensitivity.…”

Section: Resultsmentioning

confidence: 99%

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A Flexible Optoelectronic Device for Continuous Cerebral Blood Flow Monitoring

Wang

et al. 2022

Biosensors

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Human cerebral oxygenation and hemodynamics can be estimated by cerebral oxygenation parameters. Functional near-infrared spectroscopy (fNIRS) can be used to measure the hemoglobin concentration index of brain tissue noninvasively and in real time. However, limited by cumbersome equipment, high price and uncomfortable wear, conventional fNIRS monitoring systems still cannot achieve continuous and long-term monitoring. In this work, a flexible and wearable long-term monitoring system is developed featured with cost efficiency, simple preparation and light weight (only 1.6 g), which consists of a pair of light-emitting diodes (LEDs) and a photodetector (PD). Triangular serpentine interconnectors are introduced to connect the functional elements, enabling the device to be stretched in multiple directions. The device can continuously work for 7 h and be subjected to 2000 cycles of bending loading, with less than 3% change in voltage value, 1.89% and 1.9% change in LED luminous power and 0.9% change in voltage value. Furthermore, the hand-gripping and breath-holding experiments show that the system can accurately measure the changes in hemoglobin concentration in accordance with the commercial device. The flexible fNIRS system presented here not only provides a simple preparation process but also offers new ideas for daily cerebral state monitoring and prolonged clinical monitoring.

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Section: Resultsmentioning

confidence: 99%

“…The overall compact structure of the device is only 43 mm × 12 mm × 1.8 mm in size and 1.6 g in mass ( Figure S1 ). Compared with other fNIRS systems, it has the characteristics of ultrathin and ultra-soft properties, greatly improving wear comfort [ 24 ].…”

Section: Methodsmentioning

confidence: 99%

A Flexible Optoelectronic Device for Continuous Cerebral Blood Flow Monitoring

Wang

et al. 2022

Biosensors

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“…Second, it is important to note that all the information contained in NeurorehAPP will never be a substitute for professional healthcare. Further, our mobile application does not include information about the application of optical technology in the field of health care [ 31 ] or other technologies added [ 32 ], so future designs should consider these aspects. Third, although our app could be useful in addressing certain neurological diseases, its use would not always be applicable in cases where there is a cognitive impairment that hinders the understanding of the guidelines set by the application itself or in patients with motor deficits that limit the interaction with the app.…”

Section: Discussionmentioning

confidence: 99%

Designing an Informative App for Neurorehabilitation: A Feasibility and Satisfaction Study by Physiotherapists

Sánchez-Rodríguez,

Pinzón-Bernal,

Jiménez-Antona

et al. 2023

Healthcare

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Background: New technologies have gained popularity, especially the use of mobile phone applications, in neurorehabilitation. The aim of this paper was (1) to develop a free mobile application (NeurorehAPP) that provides information about and helps to select the appropriate mobile application related to a list of neurological disorders (cognitive impairment, Alzheimer’s disease, Parkinson‘s disease, multiple sclerosis, traumatic brain injury, stroke, cerebral palsy, muscular dystrophy, spina bifida, and facial paralysis), based on different objectives such as healthy habits, information, assessment, and treatment; and (2) to assess the feasibility, acceptability, and degree of satisfaction by physiotherapists after using NeurorehAPP for a minimum of three months. Methods: A free application was created to work with the Android® operating system. The degree of satisfaction and acceptance with the application was assessed with an adaptation of the Customer Satisfaction Questionnaire through a survey via email applied to physiotherapists from hospitals and neurological rehabilitation centers in Spain after using the application. Results: NeurorehAPP includes a total of 131 apps. A total of 121 physiotherapists completed a satisfaction survey. The total sample showed 85.41% satisfaction with the service provided by the app and 86.41% overall satisfaction with NeurorehAPP. Conclusions: NeurorehAPP is a free, intuitive, and friendly app used with the Android® operating system that allows the selection of the most appropriate app according to the type of user, neurological disorder, objective, and FDA criteria. Physiotherapists showed a high degree of satisfaction and acceptance with NeurorehAPP.

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Noninvasive cardiac hemodynamics monitoring of acute myocardial ischemia in rats using near‐infrared spectroscopy: A pilot study

Chen,

Li,

Pan

et al. 2024

Journal of Biophotonics

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Noninvasive and real‐time optical detection of cardiac hemodynamics dysfunction during myocardial ischemia remains challenging. In this study, we developed a near‐infrared spectroscopy device to monitor rats' myocardial hemodynamics. The well‐designed system can accurately reflect the hemodynamics changes by the classic upper limb ischemia test. Systemic hypoxia by disconnecting to the ventilator and cardiac ischemia by coronary artery slipknot ligation was conducted to monitor myocardial hemodynamics. When systemic hypoxia occurred, ΔHbR and ΔtHb increased significantly, whereas ΔHbO decreased rapidly. When coronary blood flow was obstructed by slipknots, cardiothoracic ΔHbO immediately begins to decline, while ΔHbR also significantly increases. Simultaneously, SpO2 did not show any obvious changes during myocardial ischemia, while SpO2 decreased significantly during systemic hypoxia. These results demonstrated that cardiothoracic hemodynamics stemmed from myocardial ischemia. This pilot study demonstrated the practicality of noninvasive, low‐cost optical monitoring for cardiac oxygenation dysfunction in rats.

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Performance assessment of the NIRS-based medical system of evaluating therapeutic effect

Cited by 4 publications

References 26 publications

A Flexible Optoelectronic Device for Continuous Cerebral Blood Flow Monitoring

A Flexible Optoelectronic Device for Continuous Cerebral Blood Flow Monitoring

Designing an Informative App for Neurorehabilitation: A Feasibility and Satisfaction Study by Physiotherapists

Noninvasive cardiac hemodynamics monitoring of acute myocardial ischemia in rats using near‐infrared spectroscopy: A pilot study

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