Performance evaluation for a novel optoelectronic device for noninvasive monitoring thrombosis

Zhao, Ke; Pan, Boan; Li, Zebing; Zhong, Fulin; Wang, Pengbo; Li, Ting

doi:10.1016/j.microrel.2018.03.021

Cited by 1 publication

(2 citation statements)

References 25 publications

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“…Many diseases are accompanied by abnormal tissues’ blood flow at microvascular level. Real‐time monitoring of the tissue blood flow index (BFI) would assist early detection and therapeutic assessment of the relevant diseases 1–5 . Currently, the clinical technologies available for BFI detection, such as, the ultrasound Doppler (limited to larger vessels), the laser Doppler and laser speckle imaging (limited to lower penetration depth), and the perfusion magnetic resonance imaging‐MRI (limited to heavy and expensive equipment).…”

Section: Introductionmentioning

confidence: 99%

“…Real-time monitoring of the tissue blood flow index (BFI) would assist early detection and therapeutic assessment of the relevant diseases. [1][2][3][4][5] Currently, the clinical technologies available for BFI detection, such as, the ultrasound Doppler (limited to larger vessels), the laser Doppler and laser speckle imaging (limited to lower penetration depth), and the perfusion magnetic resonance imaging-MRI (limited to heavy and expensive equipment). In recent years, a dynamic near-infrared spectroscopy (NIRS) technology, namely, diffuse correlation spectroscopy (DCS), has been rapidly developed.…”

Section: Introductionmentioning

confidence: 99%

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An extensive upgrading of contact diffuse CorrelationTomography system

Zhang,

Ding,

Shang

et al. 2024

Int J Imaging Syst Tech

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Diffuse correlation tomography (DCT) is an emerging tissue blood flow index (BFI) imaging technique that typically requires a large number of source‐detector pairs, resulting in high instrumentation costs. We developed a low‐cost paradigm for upgrading the DCT system with time‐sharing hardware sensors via optical switches, wherein the S‐D configuration was spatially optimized and combined with a novelty Nth‐order linear algorithm for image reconstruction. We verified this system through the phantom experiment and the lower limb skeletal muscle cuff occlusion test. The reconstructed BFI images exhibit the excellent performance of the upgraded DCT system in retrieval of the target location, outline, and anomaly contrast. For the deepest quasi‐solid anomaly, location accuracy was 90% with the αDB‐contrast of 0.75. While, for the deepest liquid tube anomaly, a good linear relationship was achieved between contrast and pump speed, with the αDB‐contrast of 3.29 at 600 mL/h. For human experiments, it was found that the BFI in the relaxed state was ten times higher than in the cuff occlusion state. This study demonstrates the feasibility of the proposed upgraded low‐cost DCT system for diagnosing various diseases associated with local perfusion abnormalities.

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Section: Introductionmentioning

confidence: 99%