Most Sub-Saharan Africa countries including Ghana experience a shortage of medical professionals, especially in the rural areas. This is mainly caused by the low-intake of students into medical schools due to inadequacy of facilities to train students. Also, a number of medical students graduate and emigrate to foreign countries to seek new opportunities and enhanced living standards. To reduce the effect of this, telemedicine is being implemented in certain areas to provide healthcare. Much as advances are being made in information and communication technologies, the advancement of telemedicine in developing countries still needs to upgraded and extended to cover more areas. Some categories of telemedicine have little to no implementation in Ghana due to lack of resources, little government support as well as the absence of structured frameworks and policies to ensure their implementation. This paper seeks to present telemedicine applications and implementations in Ghana till date as well as suggest some recommendations to mitigate some of the challenges impeding the advancement of telemedicine.