Performance evaluation of a gas chromatograph coupled to a capillary microwave-induced plasma mass spectrometer

Zapata, Angela María Ormaza; Bock, Christa L.; Robbat, Albert

doi:10.1039/a902656h

Cited by 9 publications

(4 citation statements)

References 20 publications

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“…To that end, chromatographic separation techniques are powerful tools in the determination of organometallic contaminants. Some recent speciation methods for organometallic compounds based on gas chromatographic (GC) separations include detection with atomic spectroscopies, including fluorescence 2-5 (AFS), absorption 6,7 (AAS), emission [8][9][10][11][12][13][14] (AES), and inductively coupled plasma (ICP) atomic emission. 15 However, there is an ever-increasing coupling of GC separations to ICP mass spectrometry [16][17][18][19][20][21][22] for speciation analysis of organometallic compounds due to several key advantages.…”

Section: Introductionmentioning

confidence: 99%

An accurate and sensitive method for the determination of methylmercury in biological specimens using GC-ICP-MS with solid phase microextraction

Davis

Pol

Schantz

et al. 2004

J. Anal. At. Spectrom.

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Section: Introductionmentioning

confidence: 99%

An accurate and sensitive method for the determination of methylmercury in biological specimens using GC-ICP-MS with solid phase microextraction

Davis

Pol

Schantz

et al. 2004

J. Anal. At. Spectrom.

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“…A detailed description of the GC/MIP-MS system is found in ref . Briefly, an Agilent pressure programmable GC, with a heated four-port solvent vent valve housed within the oven, was used.…”

Section: Methodsmentioning

confidence: 99%

“…In an earlier publication, we described a GC/MIP-MS system where a capillary MIP source operated at atmospheric pressure and, with He flow rates of 30 mL/min and 50 W power, was coupled to a mass spectrometer. Using Cl-selective detection, plasma stability was demonstrated by the excellent measurement precision, accuracy, and selectivity obtained for organochlorine pesticides detected in an extremely high hydrocarbon concentration (diesel fuel/engine oil) mixture.…”

mentioning

confidence: 99%

Performance-Enhanced “Tunable” Capillary Microwave-Induced Plasma Mass Spectrometer for Gas Chromatography Detection

Zapata

Robbat

2000

Anal. Chem.

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Improvements in the stability and performance of a capillary microwave-induced plasma-mass spectrometer (MIP-MS) were achieved by optimizing power transfer to the cavity using a tunable coaxial MIP. The MIP, operating at atmospheric pressure, was sustained with 30 mL/min He and 60 W of power. Measurement precision and sensitivity for the standard waveguide and coaxial systems were determined using 16 organochlorine pesticide solutions separated by gas chromatography (GC). The linear dynamic range obtained with the tunable MIP-MS extended over 3 orders of magnitude, a 10 time improvement with respect to the standard MIP. Detection limits were between 3 and 19 pg of Cl mol(-1) s(-1), 7 times lower than the detection limits obtained with the nontunable MIP-MS. Analysis of pesticides containing sulfur atoms was also possible, further demonstrating multielement MIP-MS detection. Excellent accuracy (10% recovery) and precision (5% RSD) were found for the detection of the pesticides in a petroleum-contaminated reference soil. By placing the GC column at the plasma expansion stage, molecular fragmentation of a mixture of volatile organic compounds was also demonstrated. With the MS operated in the selected ion monitoring mode, measurement sensitivity was approximately 500 pg/s per compound.

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“…More recently, an atmospheric pressure MIP was used as the ion source for the analysis of pesticides. 6,22 The method is particularly attractive because the microwave plasma was capable of generating simultaneous quantitative information for carbon-, chlorine-, sulfur-and phosphorus-containing molecules and also could generate molecular ions to help the identification of the parent pesticide species. Quantitative data were produced for both elemental and molecular ionization processes with the same MIP ionization source by reducing the flow rate (and without the need to re-tune the MIP cavity).…”

Section: Microwave Induced Plasmasmentioning

confidence: 99%

Plasma-based mass spectrometry for simultaneous acquisition of elemental and molecular information

Solà-Vázquez

Costa‐Fernández

Pereiro

et al. 2011

Analyst

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Chemical speciation studies are commonly accomplished by resorting to hyphenated analytical techniques, consisting of a powerful chromatographic separation technique coupled to a highly sensitive elemental spectrometric detector. However, in addition to this element-selective information, complementary molecular spectrometric tools are often required for a complete identification of macromolecules. Therefore, there is an increased research effort focused towards the development of integrated instruments to carry out the complete chemical speciation within a sample using a single instrument. An outline of recent developments in plasma-based mass spectrometric instrumentation for such comprehensive chemical speciation studies is here presented and their pros and cons detailed. In this context, the use of complementary techniques operating in parallel after splitting to a single chromatographic separation (dual sources) providing simultaneously elemental and molecular information is critically reviewed. Also, instrumental developments involving the use of stationary plasma sources operated in non-traditional modes (e.g. low pressure and low power) are also discussed. Moreover, the capabilities of tunable plasma-based ionization sources (allowing different ionization processes and, so, quasi-simultaneously providing elemental and molecular information with a single instrument) as a relatively simple and cheap approach are revised.

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Performance evaluation of a gas chromatograph coupled to a capillary microwave-induced plasma mass spectrometer

Cited by 9 publications

References 20 publications

An accurate and sensitive method for the determination of methylmercury in biological specimens using GC-ICP-MS with solid phase microextraction

An accurate and sensitive method for the determination of methylmercury in biological specimens using GC-ICP-MS with solid phase microextraction

Performance-Enhanced “Tunable” Capillary Microwave-Induced Plasma Mass Spectrometer for Gas Chromatography Detection

Plasma-based mass spectrometry for simultaneous acquisition of elemental and molecular information

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