Land-use/land cover maps constitute one of the key sources of information on urban space. To address the problems associated with the lack of timely and detailed land-use maps, the authors have developed a universal methodological approach for monitoring land use structure that is particularly useful in a rapidly evolving urban environment. Therefore, the main aim of this study was to develop a universal methodology for high-precision land-use analysis in urbanized areas in the context of large-scale mapping. The method uses geoinformation tools, photogrammetric data (orthophoto maps) as well as data acquired during a field inventory (involving a field survey and field mapping). The proposed approach is based on the modified existing approaches towards a detailed identification of land-use patterns while reducing the difficulties arising from the limitations of existing land use data sources. The methodology consists of several steps. First, the data sources for land-use analysis were selected. Subsequently, the classification of land-use categories in urban space was made. Finally, the method to high-precision land-use analysis for large-scale mapping was defined under the assumption that it is to be universal for use in countries with different levels of spatial and economic development. The proposed research method is based on an interpolation algorithm. It is highly valid, flexible, modifiable, accurate, and it can be applied to process publicly available and free sources of spatial data. Validation of the method on a test object (city of Ostróda, Poland) showed its high effectiveness, which is limited only by the type of data. The results obtained with the use of the proposed method not only supported the determination of the present land-use structure in the town but were also used to identify areas with the highest and lowest intensity and concentration of specific land-cover types.