Use of high-temperature superconductors (HTSs) for current leads to deliver power to devices at liquid helium temperature, now near commercial realization, has the potential to reduce refrigeration requirements and helium boil-off to values significantly lower than the theoretically best values achievable with conventional leads. Considerable advantage is achieved by operating these leads with an intermediate-temperature heat sink. The HTS part of the lead can be made from pressed and sintered powder. Powder-in-tube fabrication is also possible, but the normal metal part of the lead acts as a thermal short and cannot provide much stabilization without increasing the refrigeration requirement. For lead stability, designs with low current density are favored. Such leads can be manufactured with today's technology, and refrigeration requirements are lower for the same allowable burnout time. Higher current densities result in lower boil-off for the same lead length, but burnout times can be very short. In comparing experiment to theory in open systems, the density of helium vapor must be accounted for in calculating the expected boil-off. For very-low-loss leads, two-dimensional heat transfer and the state of the dewar near the leads may play dominant roles in lead performance.