Performance of 2020 AHA/ACC HCM Guidelines and Incremental Value of Myocardial Strain for Predicting SCD

Editorial echocardiography for “Incremental Value of Myocardial Global Longitudinal Strain in Predicting Major Adverse Cardiac Events Among Patients with Hypertrophic Cardiomyopathy” By Zhuang H. and colleagues

“…5 In this study, the cutoff for endoGLS to achieve a maximal AUC of 0.898 was -16%. This largely aligns with a recent cutoff of -13 % published from two prospective Korean registries by Lee et al, 7 while a meta-analysis by Tower-Rader et al reports a range of abnormal strain values (-10 to -16%) in contemporary cohorts. 4 Hence, it becomes evident that the heterogeneity and range of such optimal cutoff values need to be addressed in future larger studies.…”