The first 4 periods following use of the incentive spirometer were found to have statistically significant increases from dyspnea baseline scores (F = 77.4, P < .001). The baseline of each of the arterial blood pressure measurements, systolic, mean, and diastolic, were found to have significant differences with all of the 6 postintervention time points (systolic F = 8.0, P < .001; mean F = 7.1, P < .001; diastolic F = 7.2, P < .001). The changes in dyspnea scores and blood pressure measurements were found to have significant inverse correlations at the immediate postintervention time point (r = -0.32 to -0.35, P < .01). Results provide evidence of an inverse relationship between dyspnea and blood pressure patterns and may indicate significant clinical associations to add to the body of knowledge about the symptom of dyspnea.