Performance of an Adapted Version of the Timed Up-and-Go Test in People with Cognitive Impairments

Melo, Laura Mumic de; Ansai, Juliana Hotta; Rossi, Paulo Giusti; Vale, Francisco Assis Carvalho; Takahashi, Anielle Cristhine de Medeiros; Andrade, Larissa Pires de

doi:10.1080/00222895.2018.1552917

Cited by 22 publications

(26 citation statements)

References 28 publications

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“…However, associations were found between changes in the FAB and both the number of steps in the mild AD group and cadence in the PrC group. These findings are in agreement with the data reported by Pedroso et al 44 and Melo et al, 45 respectively. At follow-up, a decline in GS was found, while EF remained stable.…”

Section: Discussionsupporting

confidence: 94%

Changes in executive function and gait in people with mild cognitive impairment and Alzheimer disease

Cezar

Ansai

Oliveira

et al. 2021

Dement. neuropsychol.

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ABSTRACT. Changes in executive function and motor aspects can compromise the prognosis of older adults with mild cognitive impairment (MCI) and favor the evolution to dementia. Objectives: The aim of this study was to investigate the changes in executive function and gait and to determine the association between changes in these variables. Methods: A 32-month longitudinal study was conducted with 40 volunteers: 19 with preserved cognition (PrC), 15 with MCI and 6 with Alzheimer disease (AD). Executive function and gait speed were assessed using the Frontal Assessment Battery, the Clock-Drawing test and the 10-meter walk test. For data analysis, the Pearson product-moment correlation, two-way repeated-measures ANOVA, and chi-square were conducted. Results: After 32 months, an improvement in the executive function was found in all groups (p=0.003). At baseline, gait speed was slower in individuals with MCI and AD compared to those with PrC (p=0.044), that was maintained after the follow-up (p=0.001). There was significant increase in number of steps in all groups (p=0.001). No significant association was found between changes in gait speed and executive function. Conclusions: It should be taken into account that gait deteriorates prior to executive function to plan interventions and health strategies for this population.

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Section: Discussionsupporting

confidence: 94%

Changes in executive function and gait in people with mild cognitive impairment and Alzheimer disease

Cezar

Ansai

Oliveira

et al. 2021

Dement. neuropsychol.

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“…In particular, it has been observed that older adults with cognitive impairments show a higher TUG time with respect to unaffected individuals [ 21 , 22 ]. They also exhibit moderate to large correlations between cognitive performance (assessed using either Addenbrooke’s Cognitive Examination Revised ACE-R, [ 23 , 24 ] or the Montreal Cognitive Assessment, MoCA, [ 25 ]) and overall TUG time or TUG sub-phase speed (in particular intermediate and final 180° turning time [ 23 ]). The results of a recent meta-analysis [ 20 ] suggest that TUG time might be effectively employed as a marker to support the diagnosis and identification of dementia stages, including the prodromal phase.…”

Section: Introductionmentioning

confidence: 99%

Clinical assessment of gait and functional mobility in Italian healthy and cognitively impaired older persons using wearable inertial sensors

et al. 2020

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Aim The main purpose of the present study was to verify the feasibility of wearable inertial sensors (IMUs) in a clinical setting to screen gait and functional mobility in Italian older persons. In particular, we intended to verify the capability of IMUs to discriminate individuals with and without cognitive impairments and assess the existence of significant correlations between mobility parameters extracted by processing trunk accelerations and cognitive status. Methods This is a cross-sectional study performed on 213 adults aged over 65 years (mean age 77.0 ± 5.4; 62% female) who underwent cognitive assessment (through Addenbrooke’s Cognitive Examination Revised, ACE-R) instrumental gait analysis and the Timed Up and Go (TUG) test carried out using a wearable IMU located in the lower back. Results Individuals with cognitive impairments exhibit a peculiar gait pattern, characterized by significant reduction of speed (− 34% vs. healthy individuals), stride length (− 28%), cadence (− 9%), and increase in double support duration (+ 11%). Slight, but significant changes in stance and swing phase duration were also detected. Poorer performances in presence of cognitive impairment were observed in terms of functional mobility as overall and sub-phase TUG times resulted significantly higher with respect to healthy individuals (overall time, + 38%, sub-phases times ranging from + 22 to + 34%), although with some difference associated with age. The severity of mobility alterations was found moderately to strongly correlated with the ACE-R score (Spearman’s rho = 0.58 vs. gait speed, 0.54 vs. stride length, 0.66 vs. overall TUG time). Conclusion The findings obtained in the present study suggest that wearable IMUs appear to be an effective solution for the clinical assessment of mobility parameters of older persons screened for cognitive impairments within a clinical setting. They may represent a useful tool for the clinician in verifying the effectiveness of interventions to alleviate the impact of mobility limitations on daily life in cognitively impaired individuals.

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“…The majority ( n = 129, 70.5%) of the included studies' populations were older adults with no defined conditions. The remaining 54 articles (29.5%) included older adults with dementia or cognitive impairment, 34–59 fragile X syndrome associated with tremor/ataxia, a condition resulting from a gene permutation, 60 stroke, 61,62 chronic obstructive pulmonary disease, 63 cancer, 64,65 diabetes, 66 Parkinson's disease, 17,67–74 cardiovascular disease, 14,75–80 lower back pain, 81 multiple comorbidities 82–84 and post‐menopausal conditions 85 . Most studies recruited participants from the community ( n = 164, 89.6%), and the remaining studies ( n = 19, 10.4%) recruited from the hospital and long‐term care setting or both the long‐term care and community setting, or did not report the setting from which the participants were recruited.…”

Section: Resultsmentioning

confidence: 99%

“…Studies reported that better visuospatial function (e.g., higher scores in the Hooper Visual Organisation Test) was associated with faster gait speed, 93,96 completing TUG in a shorter time, 35,46 driving safely, 111 longer driving distance and time, 102 better driving scores, 34 better road test scores, 122 faster break reaction time during driving, 118 fewer driving safety errors, [123][124][125] and being less likely to fail a road test. 70 Three studies reported that a decline in visuospatial function was associated with slower gait speed, 126 completing a walking test in a longer time, 121 and failing road tests.…”

Section: Performance-basedmentioning

confidence: 99%

Cognitive, psychological and social factors associated with older adults' mobility: a scoping review of self‐report and performance‐based measures

et al. 2022

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Although many factors have been associated with mobility among older adults, there is paucity of research that explores the complexity of factors that influence mobility. This review aims to synthesise the available evidence for factors comprising the cognitive, psychological, and social mobility determinants and their associations with mobility self‐reported and performance‐based outcomes in older adults (60 years). We followed Arksey and O′Malley's five stages of a scoping review and searched PubMed, EMBASE, PsychINFO, Web of Science, AgeLine, Allied and Complementary Medicine Database, Cumulative Index to Nursing and Allied Health Literature and Sociological Abstract databases. Reviewers in pairs independently conducted title, abstract, full‐text screening and data extraction. We reported associations by analyses rather than articles because articles reported multiple associations for factors and several mobility outcomes. Associations were categorised as significantly positive, negative, or not significant. We included 183 peer‐reviewed articles published in 27 countries, most of which were cross‐sectional studies and conducted among community‐dwelling older adults. The 183 articles reported 630 analyses, of which 381 (60.5%) were significantly associated with mobility outcomes in the expected direction. For example, older adults with higher cognitive functioning such as better executive functioning had better mobility outcomes (e.g., faster gait speed), and those with poor psychological outcomes, such as depressive symptoms, or social outcomes such as reduced social network, had poorer mobility outcomes (e.g., slower gait speed) compared to their counterparts. Studies exploring the association between cognitive factors, personality (a psychological factor) and self‐reported mobility outcomes (e.g., walking for transportation or driving), and social factors and performance‐based mobility outcomes in older adults are limited. Understanding the additive relationships between cognitive, psychological, and social factors highlights the complexity of older adults' mobility across different forms of mobility, including independence, use of assistive devices, transportation, and driving.

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Performance of an Adapted Version of the Timed Up-and-Go Test in People with Cognitive Impairments

Cited by 22 publications

References 28 publications

Changes in executive function and gait in people with mild cognitive impairment and Alzheimer disease

Changes in executive function and gait in people with mild cognitive impairment and Alzheimer disease

Clinical assessment of gait and functional mobility in Italian healthy and cognitively impaired older persons using wearable inertial sensors

Cognitive, psychological and social factors associated with older adults' mobility: a scoping review of self‐report and performance‐based measures

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