Performance of and preference for oral rapid HIV testing in The Bahamas

Martin, Indira B.; Williams, V.; D, Ferguson; Read, Stanley

doi:10.1016/j.jiph.2017.06.005

Cited by 16 publications

(10 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The OraQuick ADVANCE ® Test has proven performance and patient acceptability that is facilitated by specimen flexibility ( Wesolowski et al, 2006 , Pant Pai et al, 2007 , 2012 ; Zachary et al, 2012 , Reynolds & Muwonga, 2014 , Nkenfou et al, 2014 ; Martin et al, 2017 ). The OraQuick ADVANCE ® Test is a simple, three-step protocol providing results in 20 minutes.…”

Section: Introductionmentioning

confidence: 99%

Human anti-HIV IgM detection by the OraQuick ADVANCE® Rapid HIV 1/2 Antibody Test

Guillon

Yearwood

Snipes

et al. 2018

PeerJ

View full text Add to dashboard Cite

The Centers for Disease Control and Prevention (CDC) and many public health jurisdictions continue to advocate for the most sensitive rapid HIV test that is available. Currently, the recommendation is to utilize tests that can detect HIV infection biomarkers within 30 days of infection, when initial immune responses are mounted. The infected patient’s IgM response is often used to detect acute infection within a 20–25 days window after infection. This requirement applies to lab-based testing with automated analyzers and rapid, point of care (POC) testing used for screening in a non-clinical setting. A recent study has demonstrated that POC tests using a Protein A-based detection system can detect samples with predominantly HIV-1 IgM reactivity (Moshgabadi et al., 2015). The OraQuick ADVANCE® Rapid HIV-1/2 Antibody Test (OraQuick ADVANCE®) also uses Protein A as the detection protein in the antibody-binding colloidal gold conjugate, so it is expected that the OraQuick ADVANCE® Test will also detect samples with predominantly IgM reactivity. This report definitively demonstrates that the OraQuick ADVANCE® Test can detect IgM antibodies during an acute infection window period of approximately 20–25 days after infection, and is therefore suitable for use in testing environments requiring adherence to current CDC recommendations.

show abstract

Section: Introductionmentioning

confidence: 99%

Human anti-HIV IgM detection by the OraQuick ADVANCE® Rapid HIV 1/2 Antibody Test

Guillon

Yearwood

Snipes

et al. 2018

PeerJ

View full text Add to dashboard Cite

show abstract

“…More recently, facility-based HIVST compared to provider-initiated testing and counseling was reported to increase HIV testing in a cluster-randomized trial in Malawi [36]. While several HIVST studies, including implementation science projects, have been conducted in Africa and other countries [23], our systematic review of HIV testing interventions literature in the Caribbean [37] revealed that only two studies have focused on HIVST in the Caribbean region [38,39]. Since the publication of this systematic review, results from a recent study in Puerto Rico revealed that the use of HIVST kits to screen sexual partners was acceptable and helped identify partners of positive HIV status among men who have sex with men (MSM) and transgender women, including sex workers, though some participants faced negative partner reactions when broaching the topic of HIVST [40][41][42][43][44].…”

Section: Introductionmentioning

confidence: 99%

Local and national stakeholders’ perceptions towards implementing and scaling up HIV self-testing and secondary distribution of HIV self-testing by Option B+ patients as an assisted partner service strategy to reach men in Haiti

Conserve

Michel²,

Demes

et al. 2020

PLoS ONE

View full text Add to dashboard Cite

HIV self-testing (HIVST), which allows people to test in private, is an innovative testing strategy that has been shown to increase HIV testing among men. Delivering HIVST kits to men via women is one promising assisted partner service strategy. Little research has been conducted on HIVST secondary distribution to men by women living with HIV (WLWH) in the Caribbean and other settings. The purpose of this study was to assess the perspectives of WLWH, their male partners, and healthcare professionals on the perceived advantages and disadvantages of HIVST, and recommendations for implementing HIVST in Haiti, with a focus on secondary distribution of HIVST to men by WLWH. Sixteen key informant interviews and nine focus groups with 44 healthcare workers, 31 Option B+ clients, and 13 men were carried out in Haiti. Key informants were representatives of the Ministry of Health and of a non-governmental agency involved in HIV partner services. Focus group members included program leads and staff members from the HIV care and treatment program, the Option B+ program, the community health service program, and the HIV counseling and testing services from 2 hospitals. Perceived HIVST advantage included an increase in the number of people who would learn their HIV status and start treatment. The perceived disadvantages were lack of support to ensure self-testers initiate treatment, uncertainty about male partner's reaction, risk of violence towards women delivering HIVST kits after receiving an HIVST kit from a woman, and the inability of women to counsel a man in case his selftest result is positive. Recommendations for integrating HIVST and secondary distribution of

show abstract

“…Overall, 27.1% of testers cited the convenience of getting their results on the same day as a reason for testing 38. Another article reported that participants who expressed a test preference preferred oral fluids testing to fingerprick testing (65.8% vs 34.2%) 39…”

Section: Resultsmentioning

confidence: 99%

HIV testing barriers and intervention strategies among men, transgender women, female sex workers and incarcerated persons in the Caribbean: a systematic review

et al. 2019

View full text Add to dashboard Cite

BackgroundThis systematic review summarises evidence on the HIV testing barriers and intervention strategies among Caribbean populations and provides pertinent implications for future research endeavours designed to increase rates of HIV testing in the region.MethodsWe used a systematic approach to survey all literature published between January 2008 and November 2018 using four electronic databases (MEDLINE/PubMed, Embase, Web of Science and Global Health). Only peer-reviewed articles published in English that examined HIV testing uptake and interventions in the Caribbean with men, men who have sex with men, female sex workers, transgender women and incarcerated individuals were included.ResultsTwenty-one studies met the inclusion criteria. Lack of confidentiality, access to testing sites, stigma, discrimination, poverty and low HIV risk perception were identified as key barriers to HIV testing. These barriers often contributed to late HIV testing and were associated with delayed treatment initiation and decreased survival rate. Intervention strategies to address these barriers included offering rapid HIV testing at clinics and HIV testing outreach by trained providers and peers.ConclusionHIV testing rates remain unacceptably low across the Caribbean for several reasons, including stigma and discrimination. Future HIV testing interventions should target places where at-risk populations congregate, train laypersons to conduct rapid tests and consider using oral fluid HIV self-testing, which allows individuals to test at home.

show abstract

Performance of and preference for oral rapid HIV testing in The Bahamas

Cited by 16 publications

References 18 publications

Human anti-HIV IgM detection by the OraQuick ADVANCE® Rapid HIV 1/2 Antibody Test

Human anti-HIV IgM detection by the OraQuick ADVANCE® Rapid HIV 1/2 Antibody Test

Local and national stakeholders’ perceptions towards implementing and scaling up HIV self-testing and secondary distribution of HIV self-testing by Option B+ patients as an assisted partner service strategy to reach men in Haiti

HIV testing barriers and intervention strategies among men, transgender women, female sex workers and incarcerated persons in the Caribbean: a systematic review

Contact Info

Product

Resources

About