Recent findings have shown that microbial nitrogen flow and digestible energy of diet are increased when urea (U) is combined with a slow-release urea product (SRU) in diets with a starch:acid detergent fibre (S:ADF) ratio of 4.5, while feed grade U has shown greater effects on growth performance or dietary energy utilization when the diet contains a S: ADF ratio of greater than 5.0. These results can be partially explained by the better synchronization of ruminal degradation rates between those U sources with the carbohydrates of the diets. Therefore, 60 crossbreed steers (372.4 ± 15 kg) were used to evaluate the effects of combining U and SRU in a diet with a S:ADF ratio of 4.5 vs. U that was supplemented in diets with different S:ADF ratios (3.5, 4.5 and 5.5) on growth performance, dietary energetics and carcass characteristics. U combination did not affect average daily gain (ADG), but reduced dry matter intake [DMI, as % of body weight (BW)] enough to increase feed efficiency (G:F) and dietary net energy (NE). As the S:ADF ratio increased, the DMI, ADG, G:F and NE of diet increased linearly. Irrespective of the S:ADF ratio, U diets did not modify neither the observed-to-expected NE ratio nor the apparent retention per unit DMI, while U combination increased by 7.2% and 8.4%, respectively, the observed-to-expected dietary ratio and the apparent retention per unit DMI. U combination had no effect on carcass characteristics. As the S:ADF ratio increased, carcass weight and LM area were increased linearly. Combining feed grade U and SRU in diets with a 4.5 starch:fibre ratio resulted in positive effects on the efficiency of utilization of dietary energetics.