Sore repairing since occurrence up to dry skin formation (scar) is a precious process gifted by nature. Immunology takes a predominant part in healing. A sore which is sustained just now, within minutes/hours is usually ignored till its uninterrupted scar formation. When is delayed that persists for many days, many weeks, more months, even for years is keenly noticed and is seeking secondary healing which is donated by medical men. Uninterrupted natural healing is usually processed by the immune system of the host when healing is delayed then comes interruption of the medical experts with the inclusive of medicines such as synthetic chemicals, phytotherapy, micro nano particles mingled medicines, botanical flora yield Phyto metal micro therapies which going for updated management like 3D bioprinting is in practice. An array of twenty exudates of nasal, pus, urine, stool, and blood are collected from the diverse age group of sex in various wards of SOTS (such as ICU, CCU, maternity, and casualty) from the Hospitals of Madurai. After isolating from other commensals its phenotypic character is studied through gram staining and biochemical tests. To get rid of their pathogenicity a cheap, cost-effective, eco-friendly potential medicinal ingredients possessed Amaranthaceae family yielded Alternanthera sessilis mediated fabrics coated silver nanoparticles were synthesized. In the case of MIC of AS-AgNPs against isolates zone of inhibition of the E. coli is 16mm > S. aureus is 15mm at 60µg. But in the case of MIC of fabrics against isolates the E. coli and K. oxytoca show susceptibility of 19 mm in mixed cotton. In a confirmation study of AS-AgNPs in FTIR, a sharp band is observed between 1500-500cm-1, in SEM with EDAX a graph was observed between 2.6–3.9 and black white crystals measured at 200nm in HR-TEM. Nanotechnology conjoined with herbal therapeutics provides a promising solution for wound management strategies.