Original scientific paper https://doi.org/10.2298/TSCI19S4261JIn the paper are presented the results using the authors own model to predict heat transfer coefficient during flow boiling. The model has been tested against a large selection of experimental data to investigate the sensitivity of the in-house developed model. In the work are presented the results of calculations obtained using the semi-empirical model on selected experimental flow boiling data of the refrigerants: R134a, R1234yf, R600a, R290, NH 3 , CO 2 , R236fa, R245fa, R152a, and HFE7000. In the present study, particular attention was focused on the influence of reduced pressure on the predictions of the theoretical model. The main purpose of this paper is to show the effect of the reduced pressure on the predictions of heat transfer during flow boiling.