In order to reproduce realistic human motion in a virtual environment, a study of virtual human motion control based on computer-aided ergonomics simulation is proposed. First, we establish the required human body, workpiece, and production line simulation environment, and on this basis, we use OWAS, BSHA, and other analysis tools to carry out ergonomic simulation of virtual human motion simulation research, seek solutions to man-machine problems, and provide a new, efficient, and quantitative evaluation method for production line planning. The simulation results show that during the operation of virtual human 1, the ratio of the actual load on the left and right hands to the ultimate load has reached up to 70%. Therefore, it is necessary to revise the production line plan, and through analysis, it is concluded that the reason for the bad posture is due to the low height of the storage point and the machine tool. We believe that with continuous development, ProcessSimulate and ProcessDesigner will play a greater role in enterprise digitization.