Peri-anal and genital localization of giant condyloma acuminatum or Buschke–Lowenstein’s Tumor: A report of two cases

Balla, Diop; Ba, PapaAbdoulaye; Diouf, Ahmet; NDiaye, Baba; Sarre, SerigneModou; Sylla, Chekna

doi:10.4103/jwas.jwas_5_22

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2024

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Cited by 2 publications

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“…With a 0.1 % incidence rate, GCA is further characterized clinically by its predisposition for the male, immunocompromised young adults; predilection for the genital or anorectal region; and an indolent course which may progress from the simple CA to BLT, and further with the potential for a VC [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

Surgical treatment of perineal giant condylomata acuminata (Buschke Lowenstein tumor): Case series from a developing country

Ajagbe,

Ayandipo,

Afuwape

et al. 2024

International Journal of Surgery Case Reports

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Section: Introductionmentioning

confidence: 99%

Surgical treatment of perineal giant condylomata acuminata (Buschke Lowenstein tumor): Case series from a developing country

Ajagbe,

Ayandipo,

Afuwape

et al. 2024

International Journal of Surgery Case Reports

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Buschke-Löwenstein Tumor (BLT): Successful Treatment of Human Papillomavirus (HPV)-Associated Squamous Cell Carcinoma With Radical Surgery and Chemotherapy

Baćo,

Mitric,

Mišić

et al. 2024

Cureus

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The giant condyloma acuminatum, known as the Buschke-Löwenstein tumor (BLT), is an uncommon, slow-growing, cauliflower-like tumor located in the anogenital region. It has a high recurrence rate, is sexually transmitted, and is often linked with immunosuppression. This tumor is commonly associated with human papillomavirus (HPV) infection, making HPV one of the most prevalent sexually transmitted infections affecting the perineal and genital regions. Treatment options primarily involve a combination of surgical excision and adjuvant chemotherapy. In this report, we present the case of a 63-year-old heterosexual, HIV-negative female patient whose locally advanced disease severely impacted her quality of life due to multiple bilateral perianal fistulas and the development of squamous cell carcinoma. The patient also struggled with chronic anemia resulting from recurrent hemorrhages. She underwent a Miles procedure, consisting of an extralevator abdominoperineal excision with terminal colostomy. Following adjuvant chemotherapy, she achieved complete wound healing by secondary intention, with no complications or signs of wart recurrence. This report highlights that surgical resection, complemented by adjuvant therapy, can lead to excellent outcomes even in advanced cases with local progression, regional spread, and malignant transformation, without requiring additional reconstructive surgery or skin grafting, thus facilitating recovery.

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Peri-anal and genital localization of giant condyloma acuminatum or Buschke–Lowenstein’s Tumor: A report of two cases

Cited by 2 publications

References 12 publications

Surgical treatment of perineal giant condylomata acuminata (Buschke Lowenstein tumor): Case series from a developing country

Surgical treatment of perineal giant condylomata acuminata (Buschke Lowenstein tumor): Case series from a developing country

Buschke-Löwenstein Tumor (BLT): Successful Treatment of Human Papillomavirus (HPV)-Associated Squamous Cell Carcinoma With Radical Surgery and Chemotherapy

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