Peri‐operative use of paracetamol

Oscier, Chris; Milner, Q. J. W.

doi:10.1111/j.1365-2044.2008.05674.x

Cited by 109 publications

(88 citation statements)

References 76 publications

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“…It is absorbed rapidly and well from the small intestine after oral administration with a bioavailability of between 63% and 89% (Oscier & Milner, 2009). It can also be given rectally and intravenously (see below and Section 6).…”

Section: Paracetamolmentioning

confidence: 99%

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Safety of opioid patch initiation in Australian residential aged care

Gadzhanova

Roughead

Pont

2015

Medical Journal of Australia

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Objective: To explore opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Design: A cross‐sectional cohort study, analysing pharmacy data on individual patient supply between 1 July 2008 and 30 September 2013. Setting: Sixty residential aged care facilities in New South Wales. Participants: Residents receiving an initial opioid patch during the study period. Main outcome measure: The proportion of residents who were opioid‐naive in the 4 weeks prior to patch initiation was determined. In addition, the patch strength at initiation and the daily dose of transdermal patches and of additional opioids 1 month after initiation were determined. Results: An opioid patch was initiated in 596 of 5297 residents (11.3%: 2.6% fentanyl, 8.7% buprenorphine) in the 60 residential aged care facilities. The mean age at initiation was 87 years, and 74% of the recipients were women. The proportion of recipients who were opioid‐naive before patch initiation was 34% for fentanyl and 49% for buprenorphine. Most were initiated at the lowest available patch strength, and the dose was up‐titrated after initiation. Around 15% of fentanyl users and 10% of buprenorphine users needed additional regular opioids after patch initiation. Conclusions: The results suggest some inappropriate initiation of opioid patches in Australian residential aged care facilities. Contrary to best practice, a third of residents initiated on fentanyl patches were opioid‐naive in the 4 weeks before initiation.

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Section: Paracetamolmentioning

confidence: 99%

“…The effects of the analgesics may vary with different pain models (Gray et al, 2005 Level I; Oscier & Milner, 2009 …”

Section: Chaptermentioning

confidence: 99%

Safety of opioid patch initiation in Australian residential aged care

Gadzhanova

Roughead

Pont

2015

Medical Journal of Australia

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“…The lack of a significant anti-inflammatory activity of paracetamol implies a mode of action which is distinct from that of the non-steroidal antiinflammatory drugs. Yet, the Cochrane Systematic Review, 2004 concluded that paracetamol was effective against the postoperative pain in adults [23].…”

Section: Clinical Trials On Analgesicsmentioning

confidence: 99%

The Pain Management in Orthodontics

Shenoy

Shetty

Ahmed

2013

JCDR

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Pain and discomfort are the frequent side-effects of the orthodontic therapy with fixed appliances. The people who experience orthodontic pain are likely to self-medicate with nonprescription pain relievers before seeing the dentist. It is imperative for an orthodontist to address questions that might arise in a clinical setting from the viewpoint of the clinicians and the patients/parents. This article will provide an overview of the current management strategies which are employed for alleviating orthodontic pain.

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“…Acetaminophen was selected due to its widespread use as an analgesic and because it has been thoroughly studied by many researchers. In comparison to other drugs, its systemic mechanism of action is satisfactory, although large-scale use has been shown to cause serious liver damage [14,15]. However, this side effect is not as relevant for the field of dentistry, as drugs for this use are generally administered for only a short period.…”

Section: Doi: 107243/2053-5775-1-4mentioning

confidence: 99%

Oral surgical procedures and pain, postoperative after use the ibuprofen or acetaminophen

Semenoff-Segundo¹,

Matos²,

Porto³

et al. 2013

Oral Biol Dent

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Aim: The aim of this study was to compare the effects of anti-inflammatory (ibuprofen, 600 mg) and analgesic (Acetaminophen, 750 mg) drugs on postoperative pain. Material and methods: Patients with indications for surgery were selected, and a total of 57 patients, 20 male (35.1%) and 37 female (64.9%) were included in the study. Of these, 26 patients were placed in the acetaminophen group, and 31 were placed in the ibuprofen group. The average age of the patients was 30 years. The following types of surgeries were included in the evaluation: clinical crown lengthening, gingivectomy, pre-prosthetic surgery, labial frenum and frenum lingual. The surgeries were performed by students in a postgraduate training program in periodontics. Subsequent surgery, postoperative period orientations were provided by the researcher, and the medication to be prescribed was selected at random allocation. Both medications were administered for 48-h periods. A visual analogue scale with values ranging from 0 to 10, where 0 represented no pain and 10 represented maximum pain, was provided to the patients, and the patients were asked to rate their pain using this scale each time they took the medication. At the time of the follow-up visit, the patient data were given to the researcher and subsequently tabulated and applied to the statistical analysis (Mann-Whitney, p<0.05). Results:The results showed no significant difference in pain between medications (p>0.05). Conclusions: There was no difference in postoperative periodontal surgery pain after the use of anti-inflammatory or analgesic drugs.

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Peri‐operative use of paracetamol

Cited by 109 publications

References 76 publications

Safety of opioid patch initiation in Australian residential aged care

Safety of opioid patch initiation in Australian residential aged care

The Pain Management in Orthodontics

Oral surgical procedures and pain, postoperative after use the ibuprofen or acetaminophen

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