Periampullary Gangliocytic Paraganglioma

Chiang, Ching-Shu; Shyr, Bor‐Uei; Chen, Shih‐Chin; Shyr, Yi‐Ming; Wang, Shin‐E

doi:10.1007/s11605-018-4019-z

Cited by 16 publications

(5 citation statements)

References 75 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 2 Surgery is indicated in cases of large tumor size (>2 cm), submucosal extent, periampullary location, pancreatic origin, lymph node metastasis, or suspicion of harboring malignancy. 18 Local excision is the less radical option that can be considered when lymphadenectomy is not required. 19 Pancreatoduodenectomy (open/laparoscopic/robotic) is the preferred treatment option when underlying malignancy or lymph node metastasis is suspected.…”

Section: Discussionmentioning

confidence: 99%

Gangliocytic Paraganglioma of the Duodenum: A Masquerader

Jain

Selvakumar

Varshney

et al. 2023

TOJ

View full text Add to dashboard Cite

Background: Gangliocytic paraganglioma (GP) is a rare tumor that most commonly arises from the duodenum and is characterized pathologically by 3 cell types: epithelioid, spindle, and ganglion cells. GP is often difficult to differentiate from a neuroendocrine tumor on the basis of preoperative imaging, and the diagnosis is based on final histopathologic and immunohistochemical analysis. Case Report: We report the case of a 28-year-old male who presented with pain in the abdomen, bilious vomiting, and weight loss. Imaging showed a mass involving the first and second part of the duodenum that was likely a neuroendocrine or gastrointestinal stromal tumor. He underwent robotic-assisted pancreatoduodenectomy, and the final pathology report identified GP with lymph node metastasis. The patient was doing well at 1-year follow-up. Conclusion: GP is often a histologic surprise as most cases are diagnosed in postoperative histopathology. While GP has a more benign course than a neuroendocrine tumor, radical surgical resection is warranted in cases of diagnostic dilemma, suspicion of malignancy, or lymph node metastasis. Robotic-assisted pancreatoduodenectomy is a feasible option.

show abstract

Section: Discussionmentioning

confidence: 99%

Gangliocytic Paraganglioma of the Duodenum: A Masquerader

Jain

Selvakumar

Varshney

et al. 2023

TOJ

View full text Add to dashboard Cite

show abstract

“…This article reviews 2 cases of gangliocytic paraganglioma, a rare, benign NET characterized by 3 cell types: spindle, epithelioid, and ganglion-like cells. GP commonly appears in the second and third portions of the duodenum, near the major papilla of Vater [1] . The mean age of individuals affected by GP is 53.5 years with an average tumor size of 2.6 cm, and it is slightly more prevalent in males.…”

Section: Discussionmentioning

confidence: 99%

“…Gangliocytic paraganglioma (GP) is a rare neuroendocrine tumor (NET) that commonly arises in the periampullary portion of the duodenum [1] . The GP tumor is distinguished by its triphasic cellular distinctiveness: spindle cells, endocrine cells, and ganglion cells [2] .…”

Section: Introductionmentioning

confidence: 99%

Distinct cases of gangliocytic paraganglioma in the duodenum: Two case reports

Lugo-Fagundo

Weisberg

Fishman

2022

Radiology Case Reports

View full text Add to dashboard Cite

“…Rare tumours, like gangliocytic paraganglioma, similarly to other periampullary neoplasms, usually have malignant potential, and endoscopic resection is the treatment of choice for tumours without evidence of metastasis, whereas pancreaticoduodenectomy is suggested for those with large tumour size, submucosal extent, or pancreatic GP [54].…”

Section: Gastroenterology Review 2019; 14 (4)mentioning

confidence: 99%

Benign and non-neoplastic tumours of the duodenum

Latos

Kawczyk‐Krupka

Strzelczyk³

et al. 2019

View full text Add to dashboard Cite

This review study describes the problem of duodenal tumours, which are rare but important in gastrological practice. The most common location of small intestinal tumours is the duodenum, and this observation is probably partly due to the greater diagnostic availability for most proximal segments of the small intestine. Among tumours the following should be mentionedbenign: adenomas, lipomas, haemangiomas, and leiomyomas; and malignant: malignant tumours of epithelial origin, primary gastrointestinal stromal tumours, neuroendocrine tumours and carcinoids, lymphomas, sarcomas, teratomas, and secondary metastases. Early duodenal tumour recognition, especially with histological assessment, plays a crucial diagnostic role with future therapeutic implications. In recent years the prevalence of benign duodenal tumours has been rising due to a higher level of clinicians' doubts and the convenience of gastrointestinal endoscopy; hence, knowledge of this problem is important in routine clinical practice. The method of duodenal tumour treatment should be selected on an individual basis.

show abstract

Periampullary Gangliocytic Paraganglioma

Cited by 16 publications

References 75 publications

Gangliocytic Paraganglioma of the Duodenum: A Masquerader

Gangliocytic Paraganglioma of the Duodenum: A Masquerader

Distinct cases of gangliocytic paraganglioma in the duodenum: Two case reports

Benign and non-neoplastic tumours of the duodenum

Contact Info

Product

Resources

About