Perianal Dermatitis

Agulló-Pérez, Alfredo-Daniel; Hervella‐Garcés, Marcos; Oscoz-Jaime, S.; Azcona-Rodríguez, Maialen; Larrea-García, Mónica; Yanguas-Bayona, Juan-Ignacio

doi:10.1097/der.0000000000000274

Cited by 9 publications

(13 citation statements)

References 11 publications

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“…[4] Skin lesions are frequently found at the neck (sides), ankles, scalp, vulva, extensor forearms, pubis, scrotum, and perianal. [5] Neurodermatitis affects females more than males, among all ages in the population [3] whether adults or children. [6] Certain types of neurodermatitis can be divided into primary and secondary dermatitis (eg, psoriasis).…”

Section: Introductionmentioning

confidence: 99%

“… [6] The psychogenic factors, hot water, rubbing, and scratching will induce or aggravate the condition. It was reported that compulsive habits, anxiety, venereophobia, [5] depression, and dissociative experiences contribute to the disease. [7] Patients with neurodermatitis are associated with psychosocial burden, poor flexibility, worse social relationship, sleep disturbance, and sexual dysfunction,[ 8 9 ] low quality of life.…”

Section: Introductionmentioning

confidence: 99%

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Cupping for neurodermatitis

Peng

Zhang

et al. 2020

Medicine

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Background: Neurodermatitis is a common inflammatory and allergic disease, characterized by itching and lichenification plaque. Some studies have reported cupping therapy (CT) for the treatment of neurodermatitis. However, the effectiveness and safety are still uncertain. This study aims to evaluate the efficacy and safety of CT for the treatment of patients with neurodermatitis. Methods: We will retrieve the following electronic databases systematically: Pubmed, Web of Science, Embase, the Cochrane Library, Chinese Scientific Journal Database, China National Knowledge Infrastructure Database, Chinese Biomedical Literature Database, and Wanfang database from their inception to December 2020. Other literature resources will be manually searched. Published randomized controlled trials (RCTs) and quasi-randomized controlled trials (q-RCTs) on the topic will be retrieved by 2 investigators independently. We will apply a fixed-effect model or random effect model basis on the heterogeneity test and employ with RevMan 5.3 software for data synthesis. The total clinical effective rate will be selected as the primary outcome, skin disease quality of life index score, recurrence rate, and adverse events as secondary outcomes. Results: This study will comprehensively summarize the high-quality trials to determine the efficacy and safety of CT for the treatment of patients with neurodermatitis. Conclusion: Our systematic review will present evidence for the efficacy and safety of CT to neurodermatitis patients. OSF Registration number: DOI 10.17605/OSF.IO/6DCM3.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cupping for neurodermatitis

Peng

Zhang

et al. 2020

Medicine

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“…In a series of 124 Spanish patients with chronic perianal dermatitis (>4 weeks), systematic diagnostic work-up included patch testing. This most often revealed clinically relevant contact allergy to MCI/MI ( n = 17), neomycin sulfate ( n = 11), and caine mix (not specified; n = 6); the importance of testing own culprit products (in n = 20) was stressed [ 235 ].…”

Section: Resultsmentioning

confidence: 99%

Contact Allergy: A Review of Current Problems from a Clinical Perspective

Uter

Werfel

White

et al. 2018

IJERPH

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Contact allergy is common, affecting 27% of the general population in Europe. Original publications, including case reports, published since 2016 (inclusive) were identified with the aim of collating a full review of current problems in the field. To this end, a literature search employing methods of systematic reviewing was performed in the Medline® and Web of Science™ databases on 28 January 2018, using the search terms (“contact sensitization” or “contact allergy”). Of 446 non-duplicate publications identified by above search, 147 were excluded based on scrutiny of title, abstract and key words. Of the remaining 299 examined in full text, 291 were deemed appropriate for inclusion, and main findings were summarised in topic sections. In conclusion, diverse sources of exposures to chemicals of widely-differing types and structures, continue to induce sensitisation in man and may result in allergic contact dermatitis. Many of the chemicals are “evergreen” but others are “newcomers”. Vigilance and proper investigation (patch testing) are required to detect and inform of the presence of these haptens to which our populations remain exposed.

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“…36 Perianal psoriasis is common in genital areas, but involvement of anal canal is not yet observed. 37 Psoriasis patients have a higher risk of liver abnormalities than the general population, including non-alcoholic fatty liver disease, drug-induced hepatitis, alcoholic hepatitis and neutrophilic cholangitis. 38 In a population-based cohort study, patients with more severe psoriasis, with or without psoriatic arthritis, were found to have an elevated risk for serious liver disease, including non-alcoholic fatty liver disease and cirrhosis, especially those under systemic therapy.…”

Section: Gi Involvement In Psoriasismentioning

confidence: 99%

Gastrointestinal involvement of primary skin diseases

Hsieh

Wei

et al. 2020

Acad Dermatol Venereol

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Less is known about gastrointestinal (GI) involvement of primary skin diseases due to the difference in embryology, histology, microbiology and physiology between integument and alimentary tract. Oesophagus, following the oropharyngeal mucosa, is the most common GI segment affected by primary skin diseases, especially by eosinophilic oesophagitis, lichen planus and autoimmune bullous dermatoses like pemphigus vulgaris, mucosal membrane pemphigoid and epidermolysis bullosa acquisita. Eosinophilic oesophagitis is an emerging chronic atopic disease with oesophageal dysfunction as the typical presentation, and oesophageal narrowing, rings and stricture as late complications. Oesophageal lichen planus mainly involves the proximal to mid-oesophagus in elderly aged women with long-term oral mucosal lesions. In acute attack of pemphigus vulgaris, oesophageal involvement is not uncommon but often neglected and may cause sloughing oesophagitis (oesophagitis dissecans superficialis) with acute GI bleeding in rare cases. GI manifestation of hereditary bradykininergic angio-oedema with colicky acute abdomen mostly affects small intestine, usually in the absence of pruritus or urticaria, and is more severe and long-lasting than the acquired histaminergic form. Strong evidence supports association between inflammatory bowel disease, especially Crohn disease, and hidradenitis suppurativa/acne inversa. Patients with vitiligo need surveillance of autoimmune liver disease, autoimmune atrophic gastritis or coeliac disease when corresponding symptoms become suspect. Melanoma is the most common primary tumour metastatic to the GI tract, with small intestine predominantly targeted. Gastrointestinal involvement is not uncommon in disseminated mycosis fungoides. Extramammary Paget's disease is an intraepidermal adenocarcinoma of controversial origin, and a high association between the anogenital occurrence and colorectal adenocarcinoma has been reported. As GI tract is the largest organ system with multidimensional functions, dermatologists in daily practice should be aware of the gastrointestinal morbidities related to primary skin diseases for an early diagnosis and treatment.

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Perianal Dermatitis

Cited by 9 publications

References 11 publications

Cupping for neurodermatitis

Cupping for neurodermatitis

Contact Allergy: A Review of Current Problems from a Clinical Perspective

Gastrointestinal involvement of primary skin diseases

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