Perianal pseudoverrucous papules and nodules after surgery for Hirschsprung disease

Erosive papulonodular dermatosis associated with topical benzocaine: A report of two cases and evidence that granuloma gluteale, pseudoverrucous papules, and Jacquet's erosive dermatitis are a disease spectrum

“…14 Comparison of the published reports of genitocrural irritant dermatitis variants reveals that granuloma gluteale, PPPN, and Jacquet's erosive diaper dermatitis are more similar than dissimilar, and in all likelihood may represent the same condition. 2,26 Both of our patients had clinical lesions that were very similar in appearance to granuloma gluteale infantum/adultorum, PPPN, and Jacquet's erosive diaper dermatitis. The multiple biopsy specimens taken from patient 1 demonstrate a histologic continuum ranging from primarily a dermal inflammatory reaction with vascular congestion and mild epidermal alterations to solely epidermal hyperplasia with features of lichen simplex chronicus.…”

“…[1][2][3] Granuloma gluteale is a diaper-related irritant dermatitis seen in infants that may be multifactorial in origin. Occlusion, powder, topical halogenated steroids, Candida infection, urine, and feces are all postulated to contribute to the eruption.…”

“…1,10 It may also occur in the perianal area secondary to urinary incontinence or encopresis, and is also believed to be an irritant dermatitis. 1,2,10,11 Lesions are described as ''shiny, smooth, red, moist, flat-topped and round.'' 1 There is considerable overlap in the clinical appearance of both of these conditions, yet previous reports have stressed that granuloma gluteale and PPPN are separate and distinct entities based on differences in the histopathology of the lesions.…”

Perianal pseudoverrucous papules and nodules

“…PPPN can occur in the setting of chronic irritation such as severe intractable diarrhea from any cause, short gut syndrome, following surgical colonic re-anastomosis in patients with Hirshprung's disease,[3] chronic fecal incontinence secondary to occult spinal dysraphism. [4]…”

Alliteration in medicine: a puzzling profusion of p's

“…Recent reports have described patients with perianal pseudoverrucous papules 50 51; persistent papular plaques52; pruritic purple plaques53; painless, pruritic papules54; persistent, painful plantar masses55; progressive, pigmentary purpura56; pruritic papular porokeratosis57; and pedal erosions which were painful, plaque-like and pitted 58. A final skin finding is a benign lesion of the penile corona known as pearly penile papules or pink pearly papules 59.…”