Periapical Microsurgery: An In Vivo Evaluation of Endodontic Root-End Filling Materials

Abstract

The purpose of this study was to assess the healing of periapical tissues using three different materials (IRM [L.D. Caulk Inc, Dentsply International Inc, Milford, DE], Geristore [Den-Mat, Santa Maria, CA], and MTA [ProRoot MTA; Dentsply Tulsa Dental Specialties, Tulsa, OK]) after endodontic microsurgery in an animal model. Using beagle dogs as a study model, 48 bicuspids were accessed, instrumented, and intentionally infected. The surgical procedures were performed after 30 days following the radiographic confirmation of periapical radiolucencies. The root canals were still infected and had no disinfection procedure carried out. The root ends were resected, retrograde preparations were completed, and the experimental materials were placed under surgical operating microscopy. After a period of 6 months, digital radiographic images of the periradicular areas were taken. The samples were prepared for histologic evaluation. Although Geristore showed no radiographic difference when compared with the other groups, it showed the least favorable healing in the histologic evaluation. Our histologic and radiographic results showed no statistical difference between MTA and IRM.

Mineral Trioxide Aggregate: A Comprehensive Literature Review—Part III: Clinical Applications, Drawbacks, and Mechanism of Action

“…Geristore showed the least favorable healing in the histologic evaluation; no statistical difference was noted between MTA and IRM (38).…”

“…Many investigations have compared MTA as a root-end filling material with other currently used materials (28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38). Several investigations concerned infected root canals and induced periapical lesions before filling root-end preparations with MTA (29,(33)(34)(35)37), whereas in others, periapical surgeries were performed after root canal therapy in sound, intact teeth (28,30,32).…”

Marginal Adaptation and Cytotoxicity of Bone Cement Compared with Amalgam and Mineral Trioxide Aggregate as Root-end Filling Materials

“…Positive histologic and radiographic outcomes showed that MTA was suitable root-end filling material for periradicular surgery, providing appropriate healing response from periapical tissues (3). MTA has been shown to be bioactive because of its ability to promote a biomineralization process (4).…”

A case of periradicular surgery: apicoectomy and obturation of the apex, a bold act

“…Numerous materials have been recommended for rootend obturation, and many studies have attempted to identify an ideal material; however, an ideal material has not been found. [7] The most commonly used materials are mineral trioxide aggregate (MTA) and IRM. [7] Recent studies show that although IRM achieved the most favorable healing response, both radiographically and histologically, these results were not statistically different from MTA.…”